Anti-STAG1 Antibody (CAB17315)
- SKU:
- CAB17315
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Frequently bought together:
Description
| 抗体名: | Anti-STAG1 Antibody |
| 抗体コード: | CAB17315 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 930-1140 of human STAG1 (NP_005853.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human |
| ポジティブサンプル: | HeLa, Jurkat, 293T |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 930-1140 of human STAG1 (NP_005853.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | LFNE LVQE QGPN LDRT SAHV SGIK ELAR RFAL TFGL DQIK TREA VATL HKDG IEFA FKYQ NQKG QEYP PPNL AFLE VLSE FSSK LLRQ DKKT VHSY LEKF LTEQ MMER REDV WLPL ISYR NSLV TGGE DDRM SVNS GSSS SKTS SVRN KKGR PPLH KKRV EDES LDNT WLNR TDTM IQTP GPLP APQL TSTV LREN SRPM GDQI QEPE SEH |
| 遺伝子ID: | 10274 |
| Uniprot: | Q8WVM7 |
| セルラーロケーション: | |
| 計算された分子量: | 144kDa |
| 観察された分子量: | 144kDa |
| 同義語: | STAG1, SA1, SCC3A, MRD47 |
| バックグラウンド: | This gene is a member of the SCC3 family and is expressed in the nucleus. It encodes a component of cohesin, a multisubunit protein complex that provides sister chromatid cohesion along the length of a chromosome from DNA replication through prophase and prometaphase, after which it is dissociated in preparation for segregation during anaphase. |
| UniProt Protein Function: | STAG1: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis. Belongs to the SCC3 family. |
| UniProt Protein Details: | Protein type:Apoptosis Chromosomal Location of Human Ortholog: 3q22.3 Cellular Component: nucleoplasm; chromosome; nucleus; cytosol; chromatin; chromosome, pericentric region Molecular Function:protein binding; chromatin binding Biological Process: mitosis; cell division; mitotic cell cycle; chromosome segregation |
| NCBI Summary: | This gene is a member of the SCC3 family and is expressed in the nucleus. It encodes a component of cohesin, a multisubunit protein complex that provides sister chromatid cohesion along the length of a chromosome from DNA replication through prophase and prometaphase, after which it is dissociated in preparation for segregation during anaphase. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q8WVM7 |
| NCBI GenInfo Identifier: | 209572720 |
| NCBI Gene ID: | 10274 |
| NCBI Accession: | Q8WVM7.3 |
| UniProt Secondary Accession: | Q8WVM7,O00539, Q6P275, |
| UniProt Related Accession: | Q8WVM7 |
| Molecular Weight: | 1258 |
| NCBI Full Name: | Cohesin subunit SA-1 |
| NCBI Synonym Full Names: | stromal antigen 1 |
| NCBI Official Symbol: | STAG1 |
| NCBI Official Synonym Symbols: | SA1; SCC3A |
| NCBI Protein Information: | cohesin subunit SA-1; SCC3 homolog 1; nuclear protein stromal antigen 1 |
| UniProt Protein Name: | Cohesin subunit SA-1 |
| UniProt Synonym Protein Names: | SCC3 homolog 1; Stromal antigen 1 |
| UniProt Gene Name: | STAG1 |
| UniProt Entry Name: | STAG1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using STAG1 antibody (CAB17315) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
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