Anti-ST8SIA4 Antibody (CAB6754)
- SKU:
- CAB6754
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-ST8SIA4 Antibody |
| 抗体コード: | CAB6754 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-168 of human ST8SIA4 (NP_778222.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human |
| ポジティブサンプル: | A-549, NCI-H460, HL-60 |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-168 of human ST8SIA4 (NP_778222.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | YKTK EIAR TEEH QETQ LIGD GELS LSRS LVNS SDKI IRKA GSSI FQHN VEGW KINS SLVL EIRK NILR FLDA ERDV SVVK SSFK PGDV IHYV LDRR RTLN ISHD LHSL LPEV SPMK NRRF KTCA VVGN SGIL LDSE CGKE IDSH NFVI R |
| 遺伝子ID: | 7903 |
| Uniprot: | Q92187 |
| セルラーロケーション: | Golgi apparatus membrane, Single-pass type II membrane protein |
| 計算された分子量: | 19kDa/41kDa |
| 観察された分子量: | 41kDa |
| 同義語: | ST8SIA4, PST, PST1, SIAT8D, ST8SIA-IV |
| バックグラウンド: | The protein encoded by this gene catalyzes the polycondensation of alpha-2, 8-linked sialic acid required for the synthesis of polysialic acid, a modulator of the adhesive properties of neural cell adhesion molecule (NCAM1). The encoded protein, which is a member of glycosyltransferase family 29, is a type II membrane protein that may be present in the Golgi apparatus. Two transcript variants encoding different isoforms have been found for this gene. |
| UniProt Protein Function: | ST8SIA4: Catalyzes the polycondensation of alpha-2,8-linked sialic acid required for the synthesis of polysialic acid (PSA), which is present on the embryonic neural cell adhesion molecule (N-CAM), necessary for plasticity of neural cells. Belongs to the glycosyltransferase 29 family. |
| UniProt Protein Details: | Protein type:Transferase; Glycan Metabolism - glycosphingolipid biosynthesis - ganglio series; EC 2.4.99.-; Membrane protein, integral Chromosomal Location of Human Ortholog: 5q21 Cellular Component: Golgi membrane; integral to Golgi membrane Molecular Function:alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity; sialic acid binding Biological Process: axon guidance; nervous system development; cellular protein metabolic process; dolichol-linked oligosaccharide biosynthetic process; protein modification process; protein amino acid glycosylation; protein amino acid N-linked glycosylation via asparagine; N-glycan processing; post-translational protein modification; oligosaccharide metabolic process; ganglioside biosynthetic process |
| NCBI Summary: | The protein encoded by this gene catalyzes the polycondensation of alpha-2,8-linked sialic acid required for the synthesis of polysialic acid, a modulator of the adhesive properties of neural cell adhesion molecule (NCAM1). The encoded protein, which is a member of glycosyltransferase family 29, is a type II membrane protein that may be present in the Golgi apparatus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q92187 |
| NCBI GenInfo Identifier: | 2494834 |
| NCBI Gene ID: | 7903 |
| NCBI Accession: | Q92187.1 |
| UniProt Secondary Accession: | Q92187,Q8N1F4, Q92693, A8KA07, G3V104, |
| UniProt Related Accession: | Q92187 |
| Molecular Weight: | 359 |
| NCBI Full Name: | CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase |
| NCBI Synonym Full Names: | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 |
| NCBI Official Symbol: | ST8SIA4 |
| NCBI Official Synonym Symbols: | PST; PST1; SIAT8D; ST8SIA-IV |
| NCBI Protein Information: | CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase; SIAT8-D; ST8SiaIV; sialyltransferase 8D; polysialyltransferase-1; sialytransferase St8Sia IV; sialyltransferase St8Sia IV; alpha-2,8-sialyltransferase 8D; sialyltransferase 8 (alpha-2, 8-polysialytransferase) D; CMP-N-acetylneuraminate-poly-alpha-2,8-sialyl transferase |
| UniProt Protein Name: | CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase |
| UniProt Synonym Protein Names: | Alpha-2,8-sialyltransferase 8D; Polysialyltransferase-1; Sialyltransferase 8D; SIAT8-D; Sialyltransferase St8Sia IV; ST8SiaIV |
| Protein Family: | CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase |
| UniProt Gene Name: | ST8SIA4 |
| UniProt Entry Name: | SIA8D_HUMAN |
 | Western blot analysis of extracts of various cell lines, using ST8SIA4 Antibody (CAB6754) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (RM00021)._Exposure time: 90s. |
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