Anti-ST3GAL2 Antibody (CAB13733)
- SKU:
- CAB13733
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-ST3GAL2 Antibody |
| 抗体コード: | CAB13733 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-210 of human ST3GAL2 (NP_008858.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | A-549, Mouse heart, Mouse kidney, Rat brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-210 of human ST3GAL2 (NP_008858.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | SMAT LPYL DSGA LDGT HRVK LVPG YAGL QRLS KERL SGKS CACR RCMG DAGA SDWF DSHF DGNI SPVW TREN MDLP PDVQ RWWM MLQP QFKS HNTN EVLE KLFQ IVPG ENPY RFRD PHQC RRCA VVGN SGNL RGSG YGQD VDGH NFIM RMNQ APTV GFEQ DVGS RTTH HFMY PESA KNLP A |
| 遺伝子ID: | 6483 |
| Uniprot: | Q16842 |
| セルラーロケーション: | Golgi apparatus, Golgi stack membrane, Secreted, Single-pass type II membrane protein |
| 計算された分子量: | 40kDa |
| 観察された分子量: | 40-45kDa |
| 同義語: | ST3GAL2, Gal-NAc6S, SIAT4B, ST3GALII, ST3GalA.2 |
| バックグラウンド: | The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi but can be proteolytically processed to a soluble form. This protein, which is a member of glycosyltransferase family 29, can use the same acceptor substrates as does sialyltransferase 4A. |
| UniProt Protein Function: | ST3GAL2: It may be responsible for the synthesis of the sequence NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc- found in terminal carbohydrate groups of certain glycoproteins, oligosaccharides and glycolipids. SIAT4A and SIAT4B sialylate the same acceptor substrates but exhibit different Km values. Belongs to the glycosyltransferase 29 family. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; EC 2.4.99.4; Glycan Metabolism - O-glycan biosynthesis; Glycan Metabolism - glycosphingolipid biosynthesis - globo series; Glycan Metabolism - keratan sulfate biosynthesis; Transferase; Glycan Metabolism - glycosphingolipid biosynthesis - ganglio series Chromosomal Location of Human Ortholog: 16q22.1 Cellular Component: Golgi membrane Molecular Function:beta-galactoside alpha-2,3-sialyltransferase activity Biological Process: amino sugar metabolic process; ganglioside biosynthetic process; keratan sulfate biosynthetic process; O-glycan processing; oligosaccharide metabolic process; protein amino acid N-linked glycosylation via asparagine; protein modification process |
| NCBI Summary: | The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi but can be proteolytically processed to a soluble form. This protein, which is a member of glycosyltransferase family 29, can use the same acceptor substrates as does sialyltransferase 4A. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q16842 |
| NCBI GenInfo Identifier: | 21759433 |
| NCBI Gene ID: | 6483 |
| NCBI Accession: | Q16842.1 |
| UniProt Secondary Accession: | Q16842,O00654, |
| UniProt Related Accession: | Q16842 |
| Molecular Weight: | 40,173 Da |
| NCBI Full Name: | CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 |
| NCBI Synonym Full Names: | ST3 beta-galactoside alpha-2,3-sialyltransferase 2 |
| NCBI Official Symbol: | ST3GAL2 |
| NCBI Official Synonym Symbols: | SIAT4B; ST3GALII; Gal-NAc6S; ST3GalA.2 |
| NCBI Protein Information: | CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 |
| UniProt Protein Name: | CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 |
| UniProt Synonym Protein Names: | Gal-NAc6S; Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase; ST3Gal II; ST3GalII; ST3GalA.2; Sialyltransferase 4B; SIAT4-B |
| Protein Family: | CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase |
| UniProt Gene Name: | ST3GAL2 |
| UniProt Entry Name: | SIA4B_HUMAN |
 | Western blot analysis of extracts of various cell lines, using ST3GAL2 antibody (CAB13733) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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