Anti-SSX4 Antibody (CAB7929)
- SKU:
- CAB7929
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
抗体名: | Anti-SSX4 Antibody |
抗体コード: | CAB7929 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 70-188 of human SSX4 (NP_005627.1). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse |
ポジティブサンプル: | Mouse kidney, Mouse lung |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 70-188 of human SSX4 (NP_005627.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | FMRS KRAA DFHG NDFG NDRN HRNQ VERP QMTF GSLQ RIFP KIMP KKPA EEEN GLKE VPEA SGPQ NDGK QLCP PGNP STLE KINK TSGP KRGK HAWT HRLR ERKQ LVVY EEIS DPEE DDE |
遺伝子ID: | 6759 |
Uniprot: | O60224 |
セルラーロケーション: | |
計算された分子量: | 17kDa/21kDa |
観察された分子量: | 27kDa |
同義語: | SSX4, CT5.4 |
バックグラウンド: | The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. Chromosome Xp11 contains a segmental duplication resulting in two identical copies of synovial sarcoma, X breakpoint 4, SSX4 and SSX4B, in tail-to-tail orientation. This gene, SSX4, represents the more telomeric copy. Two transcript variants encoding distinct isoforms have been identified for this gene. |
UniProt Protein Function: | SSX4: Could act as a modulator of transcription. Belongs to the SSX family. |
UniProt Protein Details: | Protein type:Cancer Testis Antigen (CTA) Chromosomal Location of Human Ortholog: Xp11.23 Cellular Component: nucleus Molecular Function:transcription corepressor activity |
NCBI Summary: | The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. Chromosome Xp11 contains a segmental duplication resulting in two identical copies of synovial sarcoma, X breakpoint 4, SSX4 and SSX4B, in tail-to-tail orientation. This gene, SSX4B, represents the more centromeric copy. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] |
UniProt Code: | O60224 |
NCBI GenInfo Identifier: | 6094362 |
NCBI Gene ID: | 548313 |
NCBI Accession: | O60224.1 |
UniProt Secondary Accession: | O60224,Q3SYD4, Q5JQZ0, Q9UJU9, A8MYD4, B2RPE3, |
UniProt Related Accession: | O60224 |
Molecular Weight: | 17,918 Da |
NCBI Full Name: | Protein SSX4 |
NCBI Synonym Full Names: | SSX family member 4B |
NCBI Official Symbol: | SSX4B |
NCBI Official Synonym Symbols: | CT5.4 |
NCBI Protein Information: | protein SSX4 |
UniProt Protein Name: | Protein SSX4 |
UniProt Synonym Protein Names: | Cancer/testis antigen 5.4; CT5.4 |
Protein Family: | Protein |
UniProt Gene Name: | SSX4 |
UniProt Entry Name: | SSX4_HUMAN |
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