Anti-SSTR5 Antibody (CAB8698)
- SKU:
- CAB8698
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Monoclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-SSTR5 Antibody |
| 抗体コード: | CAB8698 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | A synthesized peptide derived from human SSTR5 |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | HT-29, 293T, NIH/3T3, SH-SY5Y, Mouse brain, Rat brain |
| 免疫原: | A synthesized peptide derived from human SSTR5 |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 6755 |
| Uniprot: | P35346 |
| セルラーロケーション: | |
| 計算された分子量: | 42kDa |
| 観察された分子量: | 45KDa |
| 同義語: | SS-5-R |
| バックグラウンド: | Somatostatin and its related peptide cortistatin exert multiple biological actions on normal and tumoral tissue targets by interacting with somatostatin receptors (SSTRs). The protein encoded by this gene is one of the SSTRs, which is a multi-pass membrane protein and belongs to the G-protein coupled receptor 1 family. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase, and different regions of this receptor molecule are required for the activation of different signaling pathways. A mutation in this gene results in somatostatin analog resistance. Alternatively spliced transcript variants have been identified in this gene.[provided by RefSeq, Feb 2010] |
| UniProt Protein Function: | SSTR5: Receptor for somatostatin 28 and to a lesser extent for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. |
| UniProt Protein Details: | Protein type:Membrane protein, multi-pass; GPCR, family 1; Cell cycle regulation; Receptor, GPCR; Membrane protein, integral Chromosomal Location of Human Ortholog: 16p13.3 Cellular Component: neuron projection; integral to plasma membrane; plasma membrane Molecular Function:neuropeptide binding; somatostatin receptor activity Biological Process: positive regulation of cytokinesis; negative regulation of cell proliferation; G-protein signaling, coupled to cyclic nucleotide second messenger; synaptic transmission; G-protein coupled receptor protein signaling pathway; neuropeptide signaling pathway; glucose homeostasis; regulation of insulin secretion Disease: Pituitary Adenoma, Growth Hormone-secreting |
| NCBI Summary: | Somatostatin and its related peptide cortistatin exert multiple biological actions on normal and tumoral tissue targets by interacting with somatostatin receptors (SSTRs). The protein encoded by this gene is one of the SSTRs, which is a multi-pass membrane protein and belongs to the G-protein coupled receptor 1 family. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase, and different regions of this receptor molecule are required for the activation of different signaling pathways. A mutation in this gene results in somatostatin analog resistance. Alternatively spliced transcript variants have been identified in this gene.[provided by RefSeq, Feb 2010] |
| UniProt Code: | P35346 |
| NCBI GenInfo Identifier: | 12644225 |
| NCBI Gene ID: | 6755 |
| NCBI Accession: | P35346.3 |
| UniProt Secondary Accession: | P35346,P34988, Q541E0, Q9UJI5, |
| UniProt Related Accession: | P35346,AAB31829 |
| Molecular Weight: | |
| NCBI Full Name: | Somatostatin receptor type 5 |
| NCBI Synonym Full Names: | somatostatin receptor 5 |
| NCBI Official Symbol: | SSTR5 |
| NCBI Official Synonym Symbols: | SS-5-R |
| NCBI Protein Information: | somatostatin receptor type 5; somatostatin receptor subtype 5 |
| UniProt Protein Name: | Somatostatin receptor type 5 |
| UniProt Gene Name: | SSTR5 |
| UniProt Entry Name: | SSR5_HUMAN |
 | Western blot - SSTR5 Rabbit mAb (CAB8698) |
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