Anti-SSTR3 Antibody (CAB16071)
- SKU:
- CAB16071
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-SSTR3 Antibody |
| 抗体コード: | CAB16071 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 250-350 of human SSTR3 (NP_001042.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | U-87MG, LO2, Mouse brain, Rat brain, Rat spleen |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 250-350 of human SSTR3 (NP_001042.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | RSER RVTR MVVA VVAL FVLC WMPF YVLN IVNV VCPL PEEP AFFG LYFL VVAL PYAN SCAN PILY GFLS YRFK QGFR RVLL RPSR RVRS QEPT VGPP EKTE E |
| 遺伝子ID: | 6753 |
| Uniprot: | P32745 |
| セルラーロケーション: | Cell membrane, Multi-pass membrane protein |
| 計算された分子量: | 45kDa |
| 観察された分子量: | 46kDa |
| 同義語: | SSTR3, SS-3-R, SS3-R, SS3R, SSR-28 |
| バックグラウンド: | This gene encodes a member of the somatostatin receptor protein family. Somatostatins are peptide hormones that regulate diverse cellular functions such as neurotransmission, cell proliferation, and endocrine signaling as well as inhibiting the release of many hormones and other secretory proteins. Somatostatin has two active forms of 14 and 28 amino acids. The biological effects of somatostatins are mediated by a family of G-protein coupled somatostatin receptors that are expressed in a tissue-specific manner. Somatostatin receptors form homodimers and heterodimers with other members of the superfamily as well as with other G-protein coupled receptors and receptor tyrosine kinases. This protein is functionally coupled to adenylyl cyclase. Alternate splicing results in multiple transcript variants. |
| UniProt Protein Function: | SSTR3: Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. |
| UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Membrane protein, integral; GPCR, family 1; Receptor, GPCR Chromosomal Location of Human Ortholog: 22q13.1 Cellular Component: neuron projection; nonmotile primary cilium; integral to plasma membrane; cytoplasm; plasma membrane Molecular Function:neuropeptide binding; somatostatin receptor activity; protein binding Biological Process: response to starvation; synaptic transmission; negative regulation of cell proliferation; G-protein signaling, coupled to cyclic nucleotide second messenger; cell-cell signaling; neuropeptide signaling pathway; induction of apoptosis by hormones; organelle organization and biogenesis; forebrain development; cerebellum development; spermatogenesis; regulation of insulin secretion |
| NCBI Summary: | This gene encodes a member of the somatostatin receptor protein family. Somatostatins are peptide hormones that regulate diverse cellular functions such as neurotransmission, cell proliferation, and endocrine signaling as well as inhibiting the release of many hormones and other secretory proteins. Somatostatin has two active forms of 14 and 28 amino acids. The biological effects of somatostatins are mediated by a family of G-protein coupled somatostatin receptors that are expressed in a tissue-specific manner. Somatostatin receptors form homodimers and heterodimers with other members of the superfamily as well as with other G-protein coupled receptors and receptor tyrosine kinases. This protein is functionally coupled to adenylyl cyclase. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] |
| UniProt Code: | P32745 |
| NCBI GenInfo Identifier: | 4557861 |
| NCBI Gene ID: | 6753 |
| NCBI Accession: | NP_001042.1 |
| UniProt Secondary Accession: | P32745,Q53ZR7, A8K550, |
| UniProt Related Accession: | P32745 |
| Molecular Weight: | 45,847 Da |
| NCBI Full Name: | somatostatin receptor type 3 |
| NCBI Synonym Full Names: | somatostatin receptor 3 |
| NCBI Official Symbol: | SSTR3 |
| NCBI Official Synonym Symbols: | SS3R; SS3-R; SS-3-R; SSR-28 |
| NCBI Protein Information: | somatostatin receptor type 3 |
| UniProt Protein Name: | Somatostatin receptor type 3 |
| UniProt Synonym Protein Names: | SSR-28 |
| UniProt Gene Name: | SSTR3 |
| UniProt Entry Name: | SSR3_HUMAN |
 | Western blot analysis of extracts of various cell lines, using SSTR3 antibody (CAB16071) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s. |
View AllClose