Anti-SSH2 Antibody (CAB9988)
- SKU:
- CAB9988
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-SSH2 Antibody |
抗体コード: | CAB9988 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 53-202 of human SSH2 (NP_001269060.1). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | Mouse liver |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 53-202 of human SSH2 (NP_001269060.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | GAAL FLPR GNGS STPR ISHR RNKH AGDL QQHL QAMF ILLR PEDN IRLA VRLE STYQ NRTR YMVV VSTN GRQD TEES IVLG MDFS SNDS STCT MGLV LPLW SDTL IHLD GDGG FSVS TDNR VHIF KPVS VQAM WVDR DSRN KHCD VLLV EE |
遺伝子ID: | 85464 |
Uniprot: | Q76I76 |
セルラーロケーション: | Cytoplasm, cytoskeleton |
計算された分子量: | 21kDa/22kDa/51kDa/158kDa |
観察された分子量: | 158kDa |
同義語: | SSH2, SSH-2, SSH-2L |
バックグラウンド: | This gene encodes a protein tyrosine phosphatase that plays a key role in the regulation of actin filaments. The encoded protein dephosphorylates and activates cofilin, which promotes actin filament depolymerization. Alternative splicing results in multiple transcript variants. |
UniProt Protein Function: | Protein phosphatase which regulates actin filament dynamics. Dephosphorylates and activates the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Inhibitory phosphorylation of cofilin is mediated by LIMK1, which may also be dephosphorylated and inactivated by this protein. |
UniProt Protein Details: | |
NCBI Summary: | This gene encodes a protein tyrosine phosphatase that plays a key role in the regulation of actin filaments. The encoded protein dephosphorylates and activates cofilin, which promotes actin filament depolymerization. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013] |
UniProt Code: | Q76I76 |
NCBI GenInfo Identifier: | 530788323 |
NCBI Gene ID: | 85464 |
NCBI Accession: | NP_001269058.1 |
UniProt Secondary Accession: | Q76I76,Q8TDB5, Q8WYL1, Q8WYL2, Q96F40, Q96H36, Q9C0D8 |
UniProt Related Accession: | Q76I76 |
Molecular Weight: | |
NCBI Full Name: | protein phosphatase Slingshot homolog 2 isoform 1 |
NCBI Synonym Full Names: | slingshot protein phosphatase 2 |
NCBI Official Symbol: | SSH2 |
NCBI Official Synonym Symbols: | SSH-2; SSH-2L |
NCBI Protein Information: | protein phosphatase Slingshot homolog 2 |
UniProt Protein Name: | Protein phosphatase Slingshot homolog 2 |
UniProt Synonym Protein Names: | SSH-like protein 2; SSH-2L; hSSH-2L |
Protein Family: | Protein phosphatase Slingshot |
UniProt Gene Name: | SSH2 |
UniProt Entry Name: |
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