Anti-SRPR Antibody (CAB5939)
- SKU:
- CAB5939
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-SRPR Antibody |
抗体コード: | CAB5939 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human SRPR (NP_003130.2). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human |
ポジティブサンプル: | A-549, HT-1080 |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human SRPR (NP_003130.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MLDF FTIF SKGG LVLW CFQG VSDS CTGP VNAL IRSV LLQE RGGN NSFT HEAL TLKY KLDN QFEL VFVV GFQK ILTL TYVD KLID DVHR LFRD KYRT EIQQ QSAL SLLN GTFD FQND FLRL LREA EESS KIRA PTTM KKFE DSEK AKKP VRSM IETR GEKP KEKA KNSK KKGA KKEG SDGP LATS KPVP AEKS GLPV GPEN GVEL SKEE LIRR KREE FIQK |
遺伝子ID: | 6734 |
Uniprot: | P08240 |
セルラーロケーション: | Endoplasmic reticulum membrane, Peripheral membrane protein |
計算された分子量: | 66kDa/69kDa |
観察された分子量: | 75kDa |
同義語: | SRPRA, DP, SRPR, Sralpha |
バックグラウンド: | The gene encodes a subunit of the endoplasmic reticulum signal recognition particle receptor that, in conjunction with the signal recognition particle, is involved in the targeting and translocation of signal sequence tagged secretory and membrane proteins across the endoplasmic reticulum. Alternative splicing results in multiple transcript variants. |
UniProt Protein Function: | SRPR: Component of the SRP (signal recognition particle) receptor. Ensures, in conjunction with the signal recognition particle, the correct targeting of the nascent secretory proteins to the endoplasmic reticulum membrane system. Belongs to the GTP-binding SRP family. |
UniProt Protein Details: | Protein type:Endoplasmic reticulum Chromosomal Location of Human Ortholog: 11q24.2 Cellular Component: endoplasmic reticulum membrane; membrane; endoplasmic reticulum; signal recognition particle receptor complex; integral to membrane Molecular Function:GTPase activity; GTP binding; signal recognition particle binding Biological Process: SRP-dependent cotranslational protein targeting to membrane; unfolded protein response, activation of signaling protein activity; cellular protein metabolic process; translation; unfolded protein response; gene expression; cotranslational protein targeting to membrane |
NCBI Summary: | The gene encodes a subunit of the endoplasmic reticulum signal recognition particle receptor that, in conjunction with the signal recognition particle, is involved in the targeting and translocation of signal sequence tagged secretory and membrane proteins across the endoplasmic reticulum. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010] |
UniProt Code: | P08240 |
NCBI GenInfo Identifier: | 20455516 |
NCBI Gene ID: | 6734 |
NCBI Accession: | P08240.2 |
UniProt Secondary Accession: | P08240,Q9BVJ4, A6NIB3, B2R5Z8, B4E0H3, E9PJS4, |
UniProt Related Accession: | P08240 |
Molecular Weight: | 638 |
NCBI Full Name: | Signal recognition particle receptor subunit alpha |
NCBI Synonym Full Names: | signal recognition particle receptor (docking protein) |
NCBI Official Symbol: | SRPR |
NCBI Official Synonym Symbols: | DP; Sralpha |
NCBI Protein Information: | signal recognition particle receptor subunit alpha; DP-alpha; SR-alpha; SRP-alpha; docking protein alpha |
UniProt Protein Name: | Signal recognition particle receptor subunit alpha |
UniProt Synonym Protein Names: | Docking protein alpha; DP-alpha |
Protein Family: | HTH-type transcriptional regulator |
UniProt Gene Name: | SRPR |
UniProt Entry Name: | SRPR_HUMAN |
View AllClose