Anti-SQLE Antibody (CAB2428)
- SKU:
- CAB2428
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-SQLE Antibody |
| 抗体コード: | CAB2428 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC IF |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 143-400 of human SQLE (NP_003120.2). |
| 申し込み: | WB IHC IF |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:100 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | SKOV3, Mouse liver, Mouse kidney, Rat liver |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 143-400 of human SQLE (NP_003120.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | SRDG RKVT VIER DLKE PDRI VGEF LQPG GYHV LKDL GLGD TVEG LDAQ VVNG YMIH DQES KSEV QIPY PLSE NNQV QSGR AFHH GRFI MSLR KAAM AEPN AKFI EGVV LQLL EEDD VVMG VQYK DKET GDIK ELHA PLTV VADG LFSK FRKS LVSN KVSV SSHF VGFL MKNA PQFK ANHA ELIL ANPS PVLI YQIS SSET RVLV DIRG EMPR NLRE YMVE KIYP QIPD HLKE PFLE ATDN SHLR SMPA SFLP PSSV KK |
| 遺伝子ID: | 6713 |
| Uniprot: | Q14534 |
| セルラーロケーション: | Endoplasmic reticulum membrane, Microsome membrane, Multi-pass membrane protein |
| 計算された分子量: | 63kDa |
| 観察された分子量: | 71kDa |
| 同義語: | SQLE |
| バックグラウンド: | Squalene epoxidase catalyzes the first oxygenation step in sterol biosynthesis and is thought to be one of the rate-limiting enzymes in this pathway. |
| UniProt Protein Function: | SQLE: Catalyzes the first oxygenation step in sterol biosynthesis and is suggested to be one of the rate-limiting enzymes in this pathway. Belongs to the squalene monooxygenase family. |
| UniProt Protein Details: | Protein type:Lipid Metabolism - steroid biosynthesis; EC 1.14.13.132; Oxidoreductase; Endoplasmic reticulum; Membrane protein, multi-pass; Membrane protein, integral Chromosomal Location of Human Ortholog: 8q24.1 Cellular Component: endoplasmic reticulum membrane Molecular Function:squalene monooxygenase activity Biological Process: cholesterol biosynthetic process |
| NCBI Summary: | Squalene epoxidase catalyzes the first oxygenation step in sterol biosynthesis and is thought to be one of the rate-limiting enzymes in this pathway. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q14534 |
| NCBI GenInfo Identifier: | 296439362 |
| NCBI Gene ID: | 6713 |
| NCBI Accession: | Q14534.3 |
| UniProt Secondary Accession: | Q14534,Q9UEK6, |
| UniProt Related Accession: | Q14534 |
| Molecular Weight: | 63,923 Da |
| NCBI Full Name: | Squalene monooxygenase |
| NCBI Synonym Full Names: | squalene epoxidase |
| NCBI Official Symbol: | SQLE |
| NCBI Protein Information: | squalene monooxygenase |
| UniProt Protein Name: | Squalene monooxygenase |
| UniProt Synonym Protein Names: | Squalene epoxidase; SE |
| Protein Family: | Squalene monooxygenase |
| UniProt Gene Name: | SQLE |
| UniProt Entry Name: | ERG1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using SQLE antibody (CAB2428) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
View AllClose