Anti-SPTBN1 Antibody (CAB5253)
- SKU:
- CAB5253
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-SPTBN1 Antibody |
| 抗体コード: | CAB5253 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 2100-2200 of human SPTBN1 (NP_003119.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:1000 - 1:3000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | U-87MG, HeLa, Jurkat, LO2, 293T, Mouse brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 2100-2200 of human SPTBN1 (NP_003119.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | PPSP EPST KVSE EAES QQQW DTSK GEQV SQNG LPAE QGSP RMAE TVDT SEMV NGAT EQRT SSKE SSPI PSPT SDRK AKTA LPAQ SAAT LPAR TQET PSAQ M |
| 遺伝子ID: | 6711 |
| Uniprot: | Q01082 |
| セルラーロケーション: | Cell membrane, Cytoplasm, Cytoplasmic side, M line, Peripheral membrane protein, cytoskeleton, myofibril, sarcomere |
| 計算された分子量: | 251kDa/253kDa/274kDa |
| 観察された分子量: | 275kDa |
| 同義語: | SPTBN1, ELF, HEL102, SPTB2, betaSpII, spectrin beta |
| バックグラウンド: | Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is composed of two antiparallel dimers of alpha- and beta- subunits. This gene is one member of a family of beta-spectrin genes. The encoded protein contains an N-terminal actin-binding domain, and 17 spectrin repeats which are involved in dimer formation. Multiple transcript variants encoding different isoforms have been found for this gene. |
| UniProt Protein Function: | Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane. |
| NCBI Summary: | Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is composed of two antiparallel dimers of alpha- and beta- subunits. This gene is one member of a family of beta-spectrin genes. The encoded protein contains an N-terminal actin-binding domain, and 17 spectrin repeats which are involved in dimer formation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q01082 |
| NCBI GenInfo Identifier: | 116242799 |
| NCBI Gene ID: | 6711 |
| NCBI Accession: | Q01082.2 |
| UniProt Secondary Accession: | Q01082,O60837, Q16057, Q53R99, Q59ER3, Q8IX99, B2RP63 |
| UniProt Related Accession: | Q01082 |
| Molecular Weight: | 251,397 Da |
| NCBI Full Name: | Spectrin beta chain, non-erythrocytic 1 |
| NCBI Synonym Full Names: | spectrin beta, non-erythrocytic 1 |
| NCBI Official Symbol: | SPTBN1 |
| NCBI Official Synonym Symbols: | ELF; SPTB2; HEL102; betaSpII |
| NCBI Protein Information: | spectrin beta chain, non-erythrocytic 1 |
| UniProt Protein Name: | Spectrin beta chain, non-erythrocytic 1 |
| UniProt Synonym Protein Names: | Beta-II spectrin; Fodrin beta chain; Spectrin, non-erythroid beta chain 1 |
| Protein Family: | Spectrin |
| UniProt Gene Name: | SPTBN1 |
| UniProt Entry Name: | SPTB2_HUMAN |
View AllClose