Anti-SPOCK3 Antibody (CAB12849)
- SKU:
- CAB12849
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-SPOCK3 Antibody |
| 抗体コード: | CAB12849 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 180-380 of human SPOCK3 (NP_001035249.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | Mouse brain, Rat brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 180-380 of human SPOCK3 (NP_001035249.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | CPCP SDKP TSTS RNVK RACS DLEF REVA NRLR DWFK ALHE SGSQ NKKT KTLL RPER SRFD TSIL PICK DSLG WMFN RLDT NYDL LLDQ SELR SIYL DKNE QCTK AFFN SCDT YKDS LISN NEWC YCFQ RQQD PPCQ TELS NIQK RQGV KKLL GQYI PLCD EDGY YKPT QCHG SVGQ CWCV DRYG NEVM GSRI NGVA DCAI D |
| 遺伝子ID: | 50859 |
| Uniprot: | Q9BQ16 |
| セルラーロケーション: | Secreted, extracellular matrix, extracellular space |
| 計算された分子量: | 35kDa/36kDa/38kDa/44kDa/49kDa |
| 観察された分子量: | 49kDa |
| 同義語: | SPOCK3, HSAJ1454, TES-3, TICN3 |
| バックグラウンド: | This gene encodes a member of a novel family of calcium-binding proteoglycan proteins that contain thyroglobulin type-1 and Kazal-like domains. The encoded protein and may play a role in adult T-cell leukemia by inhibiting the activity of membrane-type matrix metalloproteinases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
| UniProt Protein Function: | SPOCK3: May participate in diverse steps of neurogenesis. Inhibits the processing of pro-matrix metalloproteinase 2 (MMP-2) by MT1-MMP and MT3-MMP. May interfere with tumor invasion. 4 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 4q32.3 Molecular Function:metalloendopeptidase inhibitor activity |
| NCBI Summary: | This gene encodes a member of a novel family of calcium-binding proteoglycan proteins that contain thyroglobulin type-1 and Kazal-like domains. The encoded protein and may play a role in adult T-cell leukemia by inhibiting the activity of membrane-type matrix metalloproteinases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011] |
| UniProt Code: | Q9BQ16 |
| NCBI GenInfo Identifier: | 67473703 |
| NCBI Gene ID: | 50859 |
| NCBI Accession: | Q9BQ16.2 |
| UniProt Secondary Accession: | Q9BQ16,O75705, Q6UW53, B2R7M7, B3KR67, B4DGK5, B4DHB4 B4DHV3, B4DI46, B4DJY3, E7EP61, F5H099, |
| UniProt Related Accession: | Q9BQ16 |
| Molecular Weight: | 49kDa |
| NCBI Full Name: | Testican-3 |
| NCBI Synonym Full Names: | SPARC/osteonectin, cwcv and kazal like domains proteoglycan 3 |
| NCBI Official Symbol: | SPOCK3 |
| NCBI Official Synonym Symbols: | TES-3; TICN3; HSAJ1454 |
| NCBI Protein Information: | testican-3 |
| UniProt Protein Name: | Testican-3 |
| UniProt Synonym Protein Names: | SPARC/osteonectin, CWCV, and Kazal-like domains proteoglycan 3 |
| Protein Family: | Testican |
| UniProt Gene Name: | SPOCK3 |
 | Western blot analysis of extracts of various cell lines, using SPOCK3 antibody (CAB12849) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
View AllClose