Anti-SPDYA Antibody (CAB2153)
- SKU:
- CAB2153
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Cycle
Frequently bought together:
Description
| 抗体名: | Anti-SPDYA Antibody |
| 抗体コード: | CAB2153 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-313 of human SPDYA (NP_877433.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | A-549, Mouse ovary, Rat testis |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-313 of human SPDYA (NP_877433.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MRHN QMCC ETPP TVTV YVKS GSNR SHQP KKPI TLKR PICK DNWQ AFEK NTHN NNKS KRPK GPCL VIQR QDMT AFFK LFDD DLIQ DFLW MDCC CKIA DKYL LAMT FVYF KRAK FTIS EHTR INFF IALY LANT VEED EEET KYEI FPWA LGKN WRKL FPNF LKLR DQLW DRID YRAI VSRR CCEE VMAI APTH YIWQ RERS VHHS GAVR NYNR DEVQ LPRG PSAT PVDC SLCG KKRR YVRL GLSS SSSL SSHT AGVT EKHS QDSY NSLS MDII GDPS QAYT GSEV VNDH QSNK GKKT NFLK KDKS MEWF TGSE E |
| 遺伝子ID: | 245711 |
| Uniprot: | Q5MJ70 |
| セルラーロケーション: | Nucleus |
| 計算された分子量: | 33kDa/36kDa |
| 観察された分子量: | 48kDa |
| 同義語: | SPDYA, RINGO3, RINGOA, SPDY1, SPY1 |
| バックグラウンド: |
| UniProt Protein Function: | SPDYA: Regulates the G1/S phase transition of the cell cycle by binding and activating CDK1, CDK2 and CDKN1B/KIP1. Can activate CDK2 without promoting CDK2 phosphorylation. Mediates cell survival during the DNA damage process through activation of CDK2. Belongs to the Speedy/Ringo family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 2p23.2 Cellular Component: nucleus Molecular Function:protein kinase binding Biological Process: positive regulation of cyclin-dependent protein kinase activity; multicellular organismal development; positive regulation of cell proliferation; male meiosis; response to DNA damage stimulus; G1/S transition of mitotic cell cycle |
| UniProt Code: | Q5MJ70 |
| NCBI GenInfo Identifier: | 94730574 |
| NCBI Gene ID: | 245711 |
| NCBI Accession: | Q5MJ70.2 |
| UniProt Related Accession: | Q5MJ70 |
| Molecular Weight: | 33kDa; 36kDa |
| NCBI Full Name: | Speedy protein A |
| NCBI Synonym Full Names: | speedy/RINGO cell cycle regulator family member A |
| NCBI Official Symbol: | SPDYA |
| NCBI Official Synonym Symbols: | SPY1; SPDY1; RINGO3; RINGOA |
| NCBI Protein Information: | speedy protein A |
| UniProt Protein Name: | Speedy protein A |
| UniProt Synonym Protein Names: | Rapid inducer of G2/M progression in oocytes A; RINGO A; hSpy/Ringo A; Speedy-1; Spy1 |
| Protein Family: | Speedy protein |
| UniProt Gene Name: | SPDYA |
| UniProt Entry Name: | SPDYA_HUMAN |
 | Western blot analysis of extracts of various cell lines, using SPDYA antibody (CAB2153) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 10s. |
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