Anti-SPAG5 Antibody (CAB6451)
- SKU:
- CAB6451
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Frequently bought together:
Description
| 抗体名: | Anti-SPAG5 Antibody |
| 抗体コード: | CAB6451 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | IF |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human SPAG5 (NP_006452.3). |
| 申し込み: | IF |
| 推奨希釈: | IF 1:20 - 1:50 |
| 反応性: | Human |
| ポジティブサンプル: |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human SPAG5 (NP_006452.3). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MWRV KKLS LSLS PSPQ TGKP SMRT PLRE LTLQ PGAL TNSG KRSP ACSS LTPS LCKL GLQE GSNN SSPV DFVN NKRT DLSS EHFS HSSK WLET CQHE SDEQ PLDP IPQI SSTP KTSE EAVD PLGN YMVK TIVL VPSP LGQQ QDMI FEAR LDTM AETN SISL NGPL RTDD LVRE EVAP CMGD RFSE VAAV SEKP IFQE SPSH LLEE SPPN PCSE QLHC SKES LSSR TEAV REDL VPSE SNAF LPSS VLWL SPST ALAA DFRV NHVD PEEE IVEH GAME EREM RFPT HPKE SETE DQAL VSSV |
| 遺伝子ID: | 10615 |
| Uniprot: | Q96R06 |
| セルラーロケーション: | Chromosome, Cytoplasm, Cytoplasmic granule, Midbody, centriolar satellite, centromere, centrosome, cytoskeleton, kinetochore, microtubule organizing center, spindle, spindle pole |
| 計算された分子量: | 134kDa |
| 観察された分子量: |
| 同義語: | SPAG5, DEEPEST, MAP126, hMAP126 |
| バックグラウンド: | This gene encodes a protein associated with the mitotic spindle apparatus. The encoded protein may be involved in the functional and dynamic regulation of mitotic spindles. |
| UniProt Protein Function: | SPAG5: Essential component of the mitotic spindle required for normal chromosome segregation and progression into anaphase. Required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture. The astrin (SPAG5)-kinastrin (SKAP) complex promotes stable microtubule-kinetochore attachments. |
| UniProt Protein Details: | Protein type:Cell cycle regulation Chromosomal Location of Human Ortholog: 17q11.2 Cellular Component: kinetochore; spindle microtubule Molecular Function:protein binding Biological Process: chromosome segregation; establishment of spindle orientation; mitotic sister chromatid segregation; regulation of attachment of spindle microtubules to kinetochore; spindle organization and biogenesis |
| NCBI Summary: | This gene encodes a protein associated with the mitotic spindle apparatus. The encoded protein may be involved in the functional and dynamic regulation of mitotic spindles. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q96R06 |
| NCBI GenInfo Identifier: | 47117278 |
| NCBI Gene ID: | 10615 |
| NCBI Accession: | Q96R06.2 |
| UniProt Secondary Accession: | Q96R06,O95213, Q9BWE8, Q9NT17, Q9UFE6, |
| UniProt Related Accession: | Q96R06 |
| Molecular Weight: | 134,422 Da |
| NCBI Full Name: | Sperm-associated antigen 5 |
| NCBI Synonym Full Names: | sperm associated antigen 5 |
| NCBI Official Symbol: | SPAG5 |
| NCBI Official Synonym Symbols: | MAP126; DEEPEST; hMAP126 |
| NCBI Protein Information: | sperm-associated antigen 5 |
| UniProt Protein Name: | Sperm-associated antigen 5 |
| UniProt Synonym Protein Names: | Astrin; Deepest; Mitotic spindle-associated protein p126; MAP126 |
| Protein Family: | Sperm-associated antigen |
| UniProt Gene Name: | SPAG5 |
 | Immunofluorescence analysis of HeLa cells using SPAG5 antibody (CAB6451). Blue: DAPI for nuclear staining. |
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