Anti-SOX30 Antibody (CAB11715)
- SKU:
- CAB11715
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
| 抗体名: | Anti-SOX30 Antibody |
| 抗体コード: | CAB11715 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC IF |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 604-753 of human SOX30 (NP_848511.1). |
| 申し込み: | WB IHC IF |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | U-87MG, U-251MG, Mouse testis, Mouse brain, Rat testis |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 604-753 of human SOX30 (NP_848511.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | FGTP PRFS FHHP YFLP GPHY FPSS TCPY SRPP FGYG NFPS SMPE CLSY YEDR YPKH EGIF STLN RDYS FRDY SSEC THSE NSRS CENM NGTS YYNS HSHS GEEN LNPV PQLD IGTL ENVF TAPT STPS SIQQ VNVT DSDE EEEE KVLR DL |
| 遺伝子ID: | 11063 |
| Uniprot: | O94993 |
| セルラーロケーション: | Nucleus |
| 計算された分子量: | 54kDa/81kDa |
| 観察された分子量: | 90kDa |
| 同義語: | SOX30 |
| バックグラウンド: | This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein acts as a transcriptional regulator when present in a complex with other proteins. It can activate p53 transcription to promote tumor cell apoptosis in lung cancer. The protein may be involved in the differentiation of developing male germ cells. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 5. |
| UniProt Protein Function: | SOX30: Transcriptional activator. Binds to the DNA sequence 5'- ACAAT-3' and shows a preference for guanine residues surrounding this core motif. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:DNA-binding Chromosomal Location of Human Ortholog: 5q33 Molecular Function:protein binding; sequence-specific DNA binding Biological Process: response to corticosteroid stimulus |
| NCBI Summary: | This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein acts as a transcriptional regulator when present in a complex with other proteins. It can activate p53 transcription to promote tumor cell apoptosis in lung cancer. The protein may be involved in the differentiation of developing male germ cells. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 5. [provided by RefSeq, Apr 2015] |
| UniProt Code: | O94993 |
| NCBI GenInfo Identifier: | 20532269 |
| NCBI Gene ID: | 11063 |
| NCBI Accession: | O94993.1 |
| UniProt Secondary Accession: | O94993,O94995, Q8IYX6, |
| UniProt Related Accession: | O94993 |
| Molecular Weight: | 54,290 Da |
| NCBI Full Name: | Transcription factor SOX-30 |
| NCBI Synonym Full Names: | SRY-box 30 |
| NCBI Official Symbol: | SOX30 |
| NCBI Protein Information: | transcription factor SOX-30 |
| UniProt Protein Name: | Transcription factor SOX-30 |
| Protein Family: | Transcription factor |
| UniProt Gene Name: | SOX30 |
| UniProt Entry Name: | SOX30_HUMAN |
 | Western blot analysis of extracts of various cell lines, using SOX30 antibody (CAB11715) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
View AllClose