Anti-SOX14 Antibody (CAB13674)
- SKU:
- CAB13674
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
抗体名: | Anti-SOX14 Antibody |
抗体コード: | CAB13674 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 91-240 of human SOX14 (NP_004180.1). |
申し込み: | WB IHC IF |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 91-240 of human SOX14 (NP_004180.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | RYVF PLPY LGDT DPLK AAGL PVGA SDGL LSAP EKAR AFLP PASA PYSL LDPA QFSS SAIQ KMGE VPHT LATG ALPY ASTL GYQN GAFG SLSC PSQH THTH PSPT NPGY VVPC NCTA WSAS TLQP PVAY ILFP GMTK TGID PYSS AHAT AM |
遺伝子ID: | 8403 |
Uniprot: | O95416 |
セルラーロケーション: | Nucleus |
計算された分子量: | 26kDa |
観察された分子量: | Refer to Figures |
同義語: | SOX14, SOX28 |
バックグラウンド: | This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. Mutations in this gene are suggested to be responsible for the limb defects associated with blepharophimosis, ptosis, epicanthus inversus syndrome (BPES) and Mobius syndrome. |
UniProt Protein Function: | SOX14: Acts as a negative regulator of transcription. |
UniProt Protein Details: | Protein type:DNA-binding; Transcription factor Chromosomal Location of Human Ortholog: 3q22-q23 Molecular Function:protein heterodimerization activity; sequence-specific DNA binding; chromatin binding Biological Process: transcription from RNA polymerase II promoter; nervous system development; visual perception; entrainment of circadian clock; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent |
NCBI Summary: | This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. Mutations in this gene are suggested to be responsible for the limb defects associated with blepharophimosis, ptosis, epicanthus inversus syndrome (BPES) and Mobius syndrome. [provided by RefSeq, Jul 2008] |
UniProt Code: | O95416 |
NCBI GenInfo Identifier: | 6831689 |
NCBI Gene ID: | 8403 |
NCBI Accession: | O95416.1 |
UniProt Secondary Accession: | O95416,Q3KPH7, B2RAC0, |
UniProt Related Accession: | O95416 |
Molecular Weight: | 240 |
NCBI Full Name: | Transcription factor SOX-14 |
NCBI Synonym Full Names: | SRY (sex determining region Y)-box 14 |
NCBI Official Symbol: | SOX14 |
NCBI Official Synonym Symbols: | SOX28 |
NCBI Protein Information: | transcription factor SOX-14; SRY-box 14; HMG box transcription factor SOX-14 |
UniProt Protein Name: | Transcription factor SOX-14 |
UniProt Synonym Protein Names: | Protein SOX-28 |
Protein Family: | Transcription factor |
UniProt Gene Name: | SOX14 |
UniProt Entry Name: | SOX14_HUMAN |
Immunohistochemistry of paraffin-embedded rat liver using SOX14 antibody (CAB13674) at dilution of 1:100 (40x lens). | |
Immunofluorescence analysis of MCF-7 cells using SOX14 antibody (CAB13674). |
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