Anti-SNX19 Antibody (CAB5229)
- SKU:
- CAB5229
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-SNX19 Antibody |
抗体コード: | CAB5229 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 550-750 of human SNX19 (NP_055573.2). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | SH-SY5Y, Mouse testis, Rat brain |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 550-750 of human SNX19 (NP_055573.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | HPYT LYTV KYET ALDG ENSS GLQQ LAYH TVNR RYRE FLNL QTRL EEKP DLRK FIKN VKGP KKLF PDLP FGNM DSDR VEAR KSLL ESFL KQLC AIPE IANS EEVQ EFLA LNTD ARIA FVKK PFMV SRID KMVV SAIV DTLK TAFP RSEP QSPT EELS EAET ESKP QTEG KKAS KSRL RFSS SKIS PALS VTEA QDKI LYCL Q |
遺伝子ID: | 399979 |
Uniprot: | Q92543 |
セルラーロケーション: | Cytoplasmic side, Cytoplasmic vesicle membrane, Early endosome membrane, Peripheral membrane protein |
計算された分子量: | 87kDa/108kDa |
観察された分子量: | 108kDa |
同義語: | SNX19, CHET8 |
バックグラウンド: | Islet antigen-2 (IA-2) is an autoantigen in type 1 diabetes and plays a role in insulin secretion. IA-2 is found in dense-core secretory vesicles and interacts with the product of this gene, a sorting nexin. In mouse pancreatic beta-cells, the encoded protein influenced insulin secretion by stabilizing the number of dense-core secretory vesicles. |
UniProt Protein Function: | SNX19: May be involved in several stages of intracellular trafficking. Belongs to the sorting nexin family. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 11q25 Cellular Component: cytoplasmic vesicle membrane; cytoplasm Molecular Function:protein binding; phosphoinositide binding Biological Process: insulin secretion; chondrocyte differentiation |
UniProt Code: | Q92543 |
NCBI GenInfo Identifier: | 296452910 |
NCBI Gene ID: | 399979 |
NCBI Accession: | Q92543.2 |
UniProt Secondary Accession: | Q92543,Q8IV55, E9PKB9, |
UniProt Related Accession: | Q92543 |
Molecular Weight: | 992 |
NCBI Full Name: | Sorting nexin-19 |
NCBI Synonym Full Names: | sorting nexin 19 |
NCBI Official Symbol: | SNX19 |
NCBI Official Synonym Symbols: | CHET8 |
NCBI Protein Information: | sorting nexin-19 |
UniProt Protein Name: | Sorting nexin-19 |
Protein Family: | Sorting nexin |
UniProt Gene Name: | SNX19 |
UniProt Entry Name: | SNX19_HUMAN |
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