| UniProt Protein Function: | SNTB1: Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex. Belongs to the syntrophin family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 8q23-q24 Cellular Component: dystrophin-associated glycoprotein complex; focal adhesion; protein complex Molecular Function:protein binding Biological Process: muscle contraction |
| NCBI Summary: | Dystrophin is a large, rod-like cytoskeletal protein found at the inner surface of muscle fibers. Dystrophin is missing in Duchenne Muscular Dystrophy patients and is present in reduced amounts in Becker Muscular Dystrophy patients. The protein encoded by this gene is a peripheral membrane protein found associated with dystrophin and dystrophin-related proteins. This gene is a member of the syntrophin gene family, which contains at least two other structurally-related genes. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q13884 |
| NCBI GenInfo Identifier: | 23822159 |
| NCBI Gene ID: | 6641 |
| NCBI Accession: | Q13884.3 |
| UniProt Secondary Accession: | Q13884,O14912, Q4KMG8, A8K9E0, |
| UniProt Related Accession: | Q13884 |
| Molecular Weight: | 40,805 Da |
| NCBI Full Name: | Beta-1-syntrophin |
| NCBI Synonym Full Names: | syntrophin beta 1 |
| NCBI Official Symbol: | SNTB1 |
| NCBI Official Synonym Symbols: | A1B; SNT2; BSYN2; 59-DAP; DAPA1B; SNT2B1; TIP-43 |
| NCBI Protein Information: | beta-1-syntrophin |
| UniProt Protein Name: | Beta-1-syntrophin |
| UniProt Synonym Protein Names: | 59 kDa dystrophin-associated protein A1 basic component 1; DAPA1B; BSYN2; Syntrophin-2; Tax interaction protein 43; TIP-43 |
| Protein Family: | Beta-1-syntrophin |
| UniProt Gene Name: | SNTB1 |
| UniProt Entry Name: | SNTB1_HUMAN |
