Anti-SNRNP200 Antibody (CAB6063)
- SKU:
- CAB6063
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
抗体名: | Anti-SNRNP200 Antibody |
抗体コード: | CAB6063 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1947-2136 of human SNRNP200 (NP_054733.2). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human |
ポジティブサンプル: | Jurkat, A-431, HepG2 |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1947-2136 of human SNRNP200 (NP_054733.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | QMVT QAMW SKDS YLKQ LPHF TSEH IKRC TDKG VESV FDIM EMED EERN ALLQ LTDS QIAD VARF CNRY PNIE LSYE VVDK DSIR SGGP VVVL VQLE REEE VTGP VIAP LFPQ KREE GWWV VIGD AKSN SLIS IKRL TLQQ KAKV KLDF VAPA TGAH NYTL YFMS DAYM GCDQ EYKF SVDV KEAE TDSD SD |
遺伝子ID: | 23020 |
Uniprot: | O75643 |
セルラーロケーション: | Nucleus |
計算された分子量: | 71kDa/244kDa |
観察された分子量: | 244kDa |
同義語: | SNRNP200, ASCC3L1, BRR2, HELIC2, RP33, U5-200KD, SNRNP200 |
バックグラウンド: | Pre-mRNA splicing is catalyzed by the spliceosome, a complex of specialized RNA and protein subunits that removes introns from a transcribed pre-mRNA segment. The spliceosome consists of small nuclear RNA proteins (snRNPs) U1, U2, U4, U5 and U6, together with approximately 80 conserved proteins. U5 snRNP contains nine specific proteins. This gene encodes one of the U5 snRNP-specific proteins. This protein belongs to the DEXH-box family of putative RNA helicases. It is a core component of U4/U6-U5 snRNPs and appears to catalyze an ATP-dependent unwinding of U4/U6 RNA duplices. Mutations in this gene cause autosomal-dominant retinitis pigmentosa. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined. |
UniProt Code: | O75643 |
NCBI GenInfo Identifier: | 56405304 |
NCBI Gene ID: | 23020 |
NCBI Accession: | O75643.2 |
UniProt Secondary Accession: | O75643,O94884, Q6NZY0, Q6PX59, Q8NBE6, Q96IF2, Q9H7S0 |
UniProt Related Accession: | O75643 |
Molecular Weight: | 2136 |
NCBI Full Name: | U5 small nuclear ribonucleoprotein 200 kDa helicase |
NCBI Synonym Full Names: | small nuclear ribonucleoprotein 200kDa (U5) |
NCBI Official Symbol: | SNRNP200 |
NCBI Official Synonym Symbols: | BRR2; RP33; HELIC2; ASCC3L1; U5-200KD |
NCBI Protein Information: | U5 small nuclear ribonucleoprotein 200 kDa helicase; BRR2 homolog; U5 snRNP-specific 200 kDa protein; activating signal cointegrator 1 complex subunit 3-like 1 |
UniProt Protein Name: | U5 small nuclear ribonucleoprotein 200 kDa helicase |
UniProt Synonym Protein Names: | Activating signal cointegrator 1 complex subunit 3-like 1; BRR2 homolog; U5 snRNP-specific 200 kDa protein; U5-200KD |
Protein Family: | U5 small nuclear ribonucleoprotein 200 kDa helicase |
UniProt Gene Name: | SNRNP200 |
UniProt Entry Name: | U520_HUMAN |
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