Anti-SNCG Antibody (CAB2524)
- SKU:
- CAB2524
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-SNCG Antibody |
| 抗体コード: | CAB2524 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC IF |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-127 of human SNCG (NP_003078.2). |
| 申し込み: | WB IHC IF |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | HT-29, Mouse brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-127 of human SNCG (NP_003078.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MDVF KKGF SIAK EGVV GAVE KTKQ GVTE AAEK TKEG VMYV GAKT KENV VQSV TSVA EKTK EQAN AVSE AVVS SVNT VATK TVEE AENI AVTS GVVR KEDL RPSA PQQE GEAS KEKE EVAE EAQS GGD |
| 遺伝子ID: | 6623 |
| Uniprot: | O76070 |
| セルラーロケーション: | Cytoplasm, centrosome, cytoskeleton, microtubule organizing center, perinuclear region, spindle |
| 計算された分子量: | 13kDa |
| 観察された分子量: | 13kDa |
| 同義語: | SNCG, BCSG1, SR |
| バックグラウンド: | This gene encodes a member of the synuclein family of proteins which are believed to be involved in the pathogenesis of neurodegenerative diseases. Mutations in this gene have also been associated with breast tumor development. |
| UniProt Protein Function: | SNCG: a member of the synuclein family of proteins which are believed to be involved in the pathogenesis of neurodegenerative diseases. May be involved in modulating axonal architecture during development and in the adult. Plays a role in neurofilament network integrity. High levels have been identified in advanced breast carcinomas. |
| UniProt Protein Details: | Protein type:Adaptor/scaffold Chromosomal Location of Human Ortholog: 10q23.2-q23.3 Cellular Component: cell soma; perinuclear region of cytoplasm; cytoplasm; plasma membrane; microtubule organizing center; spindle; nerve terminal Molecular Function:beta-tubulin binding; alpha-tubulin binding Biological Process: response to drug; synaptic transmission; adult locomotory behavior; protein secretion; regulation of neurotransmitter secretion; synapse organization and biogenesis; response to cocaine; regulation of dopamine secretion |
| NCBI Summary: | This gene encodes a member of the synuclein family of proteins which are believed to be involved in the pathogenesis of neurodegenerative diseases. Mutations in this gene have also been associated with breast tumor development. [provided by RefSeq, Jan 2010] |
| UniProt Code: | O76070 |
| NCBI GenInfo Identifier: | 90110074 |
| NCBI Gene ID: | 6623 |
| NCBI Accession: | O76070.2 |
| UniProt Secondary Accession: | O76070,O15104, Q96P61, |
| UniProt Related Accession: | O76070 |
| Molecular Weight: | 127 |
| NCBI Full Name: | Gamma-synuclein |
| NCBI Synonym Full Names: | synuclein, gamma (breast cancer-specific protein 1) |
| NCBI Official Symbol: | SNCG |
| NCBI Official Synonym Symbols: | SR; BCSG1 |
| NCBI Protein Information: | gamma-synuclein; persyn; synoretin; breast cancer-specific gene 1 protein |
| UniProt Protein Name: | Gamma-synuclein |
| UniProt Synonym Protein Names: | Breast cancer-specific gene 1 protein; Persyn; Synoretin; SR |
| Protein Family: | Gamma-synuclein |
| UniProt Gene Name: | SNCG |
| UniProt Entry Name: | SYUG_HUMAN |
 | Western blot analysis of extracts of various cell lines, using SNCG antibody (CAB2524) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s. |
 | Immunohistochemistry of paraffin-embedded human thyroid cancer using SNCG antibody (CAB2524) at dilution of 1:200 (40x lens). |
 | Immunofluorescence analysis of U2OS cells using SNCG antibody (CAB2524). Blue: DAPI for nuclear staining. |
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