Anti-SNAP29 Antibody (CAB19952)[KO Validated]
![Anti-SNAP29 Antibody (CAB19952)[KO Validated]](https://cdn11.bigcommerce.com/s-d5atsu6k01/images/stencil/608x608/products/25812/25660/anti-snap29-antibody-cab19952ko-validated__72827__25036.1645806346.jpg?c=1 "Anti-SNAP29 Antibody (CAB19952)[KO Validated]")
- SKU:
- CAB19952
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Autophagy
![Anti-SNAP29 Antibody (CAB19952)[KO Validated]](https://cdn11.bigcommerce.com/s-d5atsu6k01/images/stencil/1280x1280/products/25812/25660/anti-snap29-antibody-cab19952ko-validated__72827__25036.1645806346.jpg?c=1&imbypass=on "Anti-SNAP29 Antibody (CAB19952)[KO Validated]")
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Description
| 抗体名: | Anti-SNAP29 Antibody [KO Validated] |
| 抗体コード: | CAB19952 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant protein of human SNAP29. |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:1000 - 1:4000 IHC 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | HeLa |
| 免疫原: | Recombinant protein of human SNAP29. |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 9342 |
| Uniprot: | O95721 |
| セルラーロケーション: | Cell projection, Cytoplasm, Cytoplasmic vesicle, Golgi apparatus membrane, Peripheral membrane protein, autophagosome membrane, cilium membrane |
| 計算された分子量: | 28kDa |
| 観察された分子量: | 29KDa |
![Anti-SNAP29 Antibody [KO Validated] (CAB19952)](https://cdn11.bigcommerce.com/s-h68l9z2lnx/product_images/n/690/A19952_1__38048.jpg) | Western blot analysis of extracts from normal (control) and SNAP29 knockout (KO) HeLa cells, using SNAP29 antibody (CAB19952) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
| 同義語: | SNAP29, CEDNIK, SNAP-29 |
| バックグラウンド: | This gene, a member of the SNAP25 gene family, encodes a protein involved in multiple membrane trafficking steps. Two other members of this gene family, SNAP23 and SNAP25, encode proteins that bind a syntaxin protein and mediate synaptic vesicle membrane docking and fusion to the plasma membrane. The protein encoded by this gene binds tightly to multiple syntaxins and is localized to intracellular membrane structures rather than to the plasma membrane. While the protein is mostly membrane-bound, a significant fraction of it is found free in the cytoplasm. Use of multiple polyadenylation sites has been noted for this gene. |
| UniProt Protein Function: | SNAP29: Involved in multiple membrane trafficking steps. Defects in SNAP29 are the cause of CEDNIK syndrome (CEDNIK). CEDNIK is a neurocutaneous syndrome characterized by cerebral dysgenesis, neuropathy, ichthyosis and palmoplantar keratoderma. Belongs to the SNAP-25 family. |
| UniProt Protein Details: | Protein type:Vesicle Chromosomal Location of Human Ortholog: 22q11.21 Cellular Component: SNARE complex; centrosome; neuron projection; cytoplasm; plasma membrane; synapse; cell junction Molecular Function:SNAP receptor activity; syntaxin binding Biological Process: synaptic vesicle fusion to presynaptic membrane; protein transport; exocytosis; autophagic vacuole fusion; vesicle targeting; synaptic vesicle priming Disease: Cerebral Dysgenesis, Neuropathy, Ichthyosis, And Palmoplantar Keratoderma Syndrome |
| NCBI Summary: | This gene, a member of the SNAP25 gene family, encodes a protein involved in multiple membrane trafficking steps. Two other members of this gene family, SNAP23 and SNAP25, encode proteins that bind a syntaxin protein and mediate synaptic vesicle membrane docking and fusion to the plasma membrane. The protein encoded by this gene binds tightly to multiple syntaxins and is localized to intracellular membrane structures rather than to the plasma membrane. While the protein is mostly membrane-bound, a significant fraction of it is found free in the cytoplasm. Use of multiple polyadenylation sites has been noted for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O95721 |
| NCBI GenInfo Identifier: | 6685982 |
| NCBI Gene ID: | 9342 |
| NCBI Accession: | O95721.1 |
| UniProt Related Accession: | O95721 |
| Molecular Weight: | 258 |
| NCBI Full Name: | Synaptosomal-associated protein 29 |
| NCBI Synonym Full Names: | synaptosomal-associated protein, 29kDa |
| NCBI Official Symbol: | SNAP29 |
| NCBI Official Synonym Symbols: | CEDNIK; SNAP-29 |
| NCBI Protein Information: | synaptosomal-associated protein 29; soluble 29 kDa NSF attachment protein; synaptosomal-associated protein, 29kD; vesicle-membrane fusion protein SNAP-29 |
| UniProt Protein Name: | Synaptosomal-associated protein 29 |
| UniProt Synonym Protein Names: | Soluble 29 kDa NSF attachment protein; Vesicle-membrane fusion protein SNAP-29 |
| Protein Family: | SNAP25 homologous protein |
| UniProt Gene Name: | SNAP29 |
| UniProt Entry Name: | SNP29_HUMAN |