Anti-SMYD3 Antibody (CAB14516)
- SKU:
- CAB14516
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-SMYD3 Antibody |
抗体コード: | CAB14516 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human SMYD3 (NP_001161212.1). |
申し込み: | WB IHC IF |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | 22Rv1, HT-29, HepG2, MCF7, HeLa, Mouse testis |
免疫原: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human SMYD3 (NP_001161212.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | DRCL LGKE KLMR CSQC RVAK YCSA KCQK KAWP DHKR ECKC LKSC KPRY PPDS VRLL GRVV FKLM DGAP SESE KLYS FYDL ESNI NKLT EDKK EGLR QLVM T |
遺伝子ID: | 64754 |
Uniprot: | Q9H7B4 |
セルラーロケーション: | Cytoplasm, Nucleus |
計算された分子量: | 29kDa/42kDa/49kDa |
観察された分子量: | 49kDa |
同義語: | SMYD3, KMT3E, ZMYND1, ZNFN3A1, bA74P14.1 |
バックグラウンド: | This gene encodes a histone methyltransferase which functions in RNA polymerase II complexes by an interaction with a specific RNA helicase. Multiple transcript variants encoding different isoforms have been found for this gene. |
UniProt Protein Function: | SMYD3: Histone methyltransferase. Specifically methylates 'Lys- 4' of histone H3, inducing di- and tri-methylation, but not monomethylation. Plays an important role in transcriptional activation as a member of an RNA polymerase complex. Binds DNA containing 5'-CCCTCC-3' or 5'-GAGGGG-3' sequences. Belongs to the histone-lysine methyltransferase family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:EC 2.1.1.43; Methyltransferase, protein lysine; Methyltransferase Chromosomal Location of Human Ortholog: 1q44 Cellular Component: nucleoplasm; cytoplasm Molecular Function:metal ion binding; histone-lysine N-methyltransferase activity Biological Process: nucleosome assembly; establishment and/or maintenance of chromatin architecture; establishment of protein localization; myotube cell development; negative regulation of protein kinase activity; positive regulation of transcription from RNA polymerase II promoter; positive regulation of peptidyl-serine phosphorylation |
NCBI Summary: | This gene encodes a histone methyltransferase which functions in RNA polymerase II complexes by an interaction with a specific RNA helicase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011] |
UniProt Code: | Q9H7B4 |
NCBI GenInfo Identifier: | 212276523 |
NCBI Gene ID: | 64754 |
NCBI Accession: | Q9H7B4.4 |
UniProt Secondary Accession: | Q9H7B4,Q86TL8, Q8N5Z6, Q96AI5, A8K0P0, B1AN38, |
UniProt Related Accession: | Q9H7B4 |
Molecular Weight: | 428 |
NCBI Full Name: | Histone-lysine N-methyltransferase SMYD3 |
NCBI Synonym Full Names: | SET and MYND domain containing 3 |
NCBI Official Symbol: | SMYD3 |
NCBI Official Synonym Symbols: | KMT3E; ZMYND1; ZNFN3A1; bA74P14.1 |
NCBI Protein Information: | histone-lysine N-methyltransferase SMYD3; bA74P14.1 (novel protein); zinc finger, MYND domain containing 1; SET and MYND domain-containing protein 3; zinc finger MYND domain-containing protein 1; zinc finger protein, subfamily 3A (MYND domain containing) |
UniProt Protein Name: | Histone-lysine N-methyltransferase SMYD3 |
UniProt Synonym Protein Names: | SET and MYND domain-containing protein 3; Zinc finger MYND domain-containing protein 1 |
Protein Family: | Histone-lysine N-methyltransferase |
UniProt Gene Name: | SMYD3 |
UniProt Entry Name: | SMYD3_HUMAN |
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