Anti-SMPX Antibody (CAB6744)
- SKU:
- CAB6744
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-SMPX Antibody |
| 抗体コード: | CAB6744 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IF |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-88 of human SMPX (NP_055147.1). |
| 申し込み: | WB IF |
| 推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:100 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | Mouse heart, Rat heart |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-88 of human SMPX (NP_055147.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MNMS KQPV SNVR AIQA NINI PMGA FRPG AGQP PRRK ECTP EVEE GVPP TSDE EKKP IPGA KKLP GPAV NLSE IQNI KSEL KYVP KAEQ |
| 遺伝子ID: | 23676 |
| Uniprot: | Q9UHP9 |
| セルラーロケーション: | |
| 計算された分子量: | 9kDa |
| 観察された分子量: | 13kDa |
| 同義語: | SMPX, DFN6, DFNX4 |
| バックグラウンド: | This gene encodes a small protein that has no known functional domains. Mutations in this gene are a cause of X-linked deafness-4, and the encoded protein may play a role in the maintenance of inner ear cells subjected to mechanical stress. Alternatively spliced transcript variants have been observed for this gene. |
| UniProt Protein Function: | SMPX: Plays a role in the regulatory network through which muscle cells coordinate their structural and functional states during growth, adaptation, and repair. Defects in SMPX are the cause of deafness X-linked type 4 (DFNX4). A non-syndromic form of sensorineural, progressive hearing loss with postlingual onset. In affected males, the auditory impairment affects initially high-frequency hearing. It later evolves to become severe to profound and affects all frequencies. Carrier females manifest moderate hearing impairment in the high frequencies. Belongs to the SMPX family. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: Xp22.1 Cellular Component: muscle tendon junction; costamere; M band; nucleus Biological Process: striated muscle contraction Disease: Deafness, X-linked 4 |
| NCBI Summary: | This gene encodes a small protein that has no known functional domains. Mutations in this gene are a cause of X-linked deafness-4, and the encoded protein may play a role in the maintenance of inner ear cells subjected to mechanical stress. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2011] |
| UniProt Code: | Q9UHP9 |
| NCBI GenInfo Identifier: | 239938852 |
| NCBI Gene ID: | 23676 |
| NCBI Accession: | Q9UHP9.3 |
| UniProt Secondary Accession: | Q9UHP9,B1AWX2, |
| UniProt Related Accession: | Q9UHP9 |
| Molecular Weight: | 88 |
| NCBI Full Name: | Small muscular protein |
| NCBI Synonym Full Names: | small muscle protein, X-linked |
| NCBI Official Symbol: | SMPX |
| NCBI Official Synonym Symbols: | DFN6; DFNX4 |
| NCBI Protein Information: | small muscular protein; deafness, X-linked 6, sensorineural; stretch-responsive skeletal muscle protein |
| UniProt Protein Name: | Small muscular protein |
| UniProt Synonym Protein Names: | Stretch-responsive skeletal muscle protein |
| Protein Family: | Small muscular protein |
| UniProt Gene Name: | SMPX |
| UniProt Entry Name: | SMPX_HUMAN |
 | Western blot analysis of extracts of various cell lines, using SMPX antibody (CAB6744) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (RM00021)._Exposure time: 90s. |
 | Immunofluorescence analysis of MCF7 cells using SMPX antibody (CAB6744). Blue: DAPI for nuclear staining. |
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