Anti-SLU7 Antibody (CAB17614)
- SKU:
- CAB17614
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
| 抗体名: | Anti-SLU7 Antibody |
| 抗体コード: | CAB17614 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human SLU7 (NP_006416.3). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | Mouse testis, Mouse lung, Rat spleen, Rat lung |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human SLU7 (NP_006416.3). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MSAT VVDA VNAA PLSG SKEM SLEE PKKM TRED WRKK KELE EQRK LGNA PAEV DEEG KDIN PHIP QYIS SVPW YIDP SKRP TLKH QRPQ PEKQ KQFS SSGE WYKR GVKE NSII TKYR KGAC ENCG AMTH KKKD CFER PRRV GAKF TGTN IAPD EHVQ PQLM FDYD GKRD RWNG YNPE EHMK IVEE YAKV DLAK RTLK AQKL QEEL ASGK LVEQ ANSP KHQW GEEE PNSQ MEKD HNSE DEDE DKYA DDID MPGQ NFDS KRRI TVRN LRIR EDIA KYLR NLDP NSAY YDPK TRAM RENP YANA |
| 遺伝子ID: | 10569 |
| Uniprot: | O95391 |
| セルラーロケーション: | |
| 計算された分子量: | |
| 観察された分子量: | 68kDa |
 | Western blot - SLU7 Polyclonal Antibody (CAB17614) |
| 同義語: | 9G8, hSlu7, SLU7 |
| バックグラウンド: | Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is a splicing factor that has been found to be essential during the second catalytic step in the pre-mRNA splicing process. It associates with the spliceosome and contains a zinc knuckle motif that is found in other splicing factors and is involved in protein-nucleic acid and protein-protein interactions. [provided by RefSeq, Jul 2008] |
| UniProt Protein Function: | SLU7: Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'- splice site to generate spliced mRNA and the excised lariat intron. Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3'-splicing site region. May be involved in the activation of proximal AG. Probably also involved in alternative splicing regulation. Belongs to the SLU7 family. |
| UniProt Protein Details: | Protein type:Spliceosome; RNA splicing; RNA processing Chromosomal Location of Human Ortholog: 5q33.3 Cellular Component: cytoplasm; intracellular membrane-bound organelle; membrane; nuclear speck; nucleoplasm; nucleus; small nuclear ribonucleoprotein complex; spliceosome Molecular Function:pre-mRNA 3'-splice site binding; protein binding; second spliceosomal transesterification activity; zinc ion binding Biological Process: alternative nuclear mRNA splicing, via spliceosome; intracellular protein transport; mRNA 3'-end processing; mRNA export from nucleus; nuclear mRNA 3'-splice site recognition; nuclear mRNA splicing, via spliceosome; RNA export from nucleus; RNA splicing, via transesterification reactions; termination of RNA polymerase II transcription |
| NCBI Summary: | Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is a splicing factor that has been found to be essential during the second catalytic step in the pre-mRNA splicing process. It associates with the spliceosome and contains a zinc knuckle motif that is found in other splicing factors and is involved in protein-nucleic acid and protein-protein interactions. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O95391 |
| NCBI GenInfo Identifier: | 262527559 |
| NCBI Gene ID: | 10569 |
| NCBI Accession: | O95391.2 |
| UniProt Secondary Accession: | O95391,Q3LUJ0, Q3LUJ1, Q6RXQ5, Q96FM9, D3DQK2, |
| UniProt Related Accession: | O95391 |
| Molecular Weight: | 68,387 Da |
| NCBI Full Name: | Pre-mRNA-splicing factor SLU7 |
| NCBI Synonym Full Names: | SLU7 homolog, splicing factor |
| NCBI Official Symbol: | SLU7 |
| NCBI Official Synonym Symbols: | 9G8; hSlu7 |
| NCBI Protein Information: | pre-mRNA-splicing factor SLU7 |
| UniProt Protein Name: | Pre-mRNA-splicing factor SLU7 |
| Protein Family: | Pre-mRNA-splicing factor |
| UniProt Gene Name: | SLU7 |
| UniProt Entry Name: | SLU7_HUMAN |