Anti-SLITRK6 Antibody (CAB3521)
- SKU:
- CAB3521
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-SLITRK6 Antibody |
| 抗体コード: | CAB3521 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 621-816 of human SLITRK6 (NP_115605.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | 293T, Mouse brain, Rat brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 621-816 of human SLITRK6 (NP_115605.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | IVFC AAGI VVLV LHRR RRYK KKQV DEQM RDNS PVHL QYSM YGHK TTHH TTER PSAS LYEQ HMVS PMVH VYRS PSFG PKHL EEEE ERNE KEGS DAKH LQRS LLEQ ENHS PLTG SNMK YKTT NQST EFLS FQDA SSLY RNIL EKER ELQQ LGIT EYLR KNIA QLQP DMEA HYPG AHEE LKLM ETLM YSRP RKVL VEQT |
| 遺伝子ID: | 84189 |
| Uniprot: | Q9H5Y7 |
| セルラーロケーション: | Cell membrane, Single-pass type I membrane protein |
| 計算された分子量: | 95kDa |
| 観察された分子量: | 120kDa |
| 同義語: | SLITRK6, DFNMYP |
| バックグラウンド: | This gene encodes a member of the SLITRK protein family. Members of this family are integral membrane proteins that are characterized by two N-terminal leucine-rich repeat (LRR) domains and a C-terminal region that shares homology with trk neurotrophin receptors. This protein functions as a regulator of neurite outgrowth required for normal hearing and vision. Mutations in this gene are a cause of myopia and deafness. |
| UniProt Protein Function: | SLITRK6: Suppresses neurite outgrowth. Belongs to the SLITRK family. |
| UniProt Protein Details: | Protein type:Cell surface; Membrane protein, integral Chromosomal Location of Human Ortholog: 13q31.1 Cellular Component: cell surface; integral to plasma membrane Biological Process: lens development in camera-type eye; vestibulocochlear nerve development; sensory perception of sound; synaptogenesis; startle response; axonogenesis; visual perception; adult locomotory behavior; multicellular organism growth; auditory receptor cell morphogenesis; auditory behavior; linear vestibuloocular reflex Disease: Deafness And Myopia |
| NCBI Summary: | This gene encodes a member of the SLITRK protein family. Members of this family are integral membrane proteins that are characterized by two N-terminal leucine-rich repeat (LRR) domains and a C-terminal region that shares homology with trk neurotrophin receptors. This protein functions as a regulator of neurite outgrowth required for normal hearing and vision. Mutations in this gene are a cause of myopia and deafness. [provided by RefSeq, Dec 2014] |
| UniProt Code: | Q9H5Y7 |
| NCBI GenInfo Identifier: | 59803110 |
| NCBI Gene ID: | 84189 |
| NCBI Accession: | Q9H5Y7.3 |
| UniProt Secondary Accession: | Q9H5Y7,Q495Q0, Q6AW93, Q9HAA8, Q9NT60, A8K9S8, |
| UniProt Related Accession: | Q9H5Y7 |
| Molecular Weight: | |
| NCBI Full Name: | SLIT and NTRK-like protein 6 |
| NCBI Synonym Full Names: | SLIT and NTRK-like family, member 6 |
| NCBI Official Symbol: | SLITRK6 |
| NCBI Official Synonym Symbols: | DFNMYP |
| NCBI Protein Information: | SLIT and NTRK-like protein 6; 4832410J21Rik; slit and trk like gene 6 |
| UniProt Protein Name: | SLIT and NTRK-like protein 6 |
| Protein Family: | SLIT and NTRK-like protein |
| UniProt Gene Name: | SLITRK6 |
| UniProt Entry Name: | SLIK6_HUMAN |
 | Western blot analysis of extracts of various cell lines, using SLITRK6 antibody (CAB3521) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s. |
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