Anti-SLCO3A1 Antibody (CAB14276)
- SKU:
- CAB14276
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
| 抗体名: | Anti-SLCO3A1 Antibody |
| 抗体コード: | CAB14276 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 440-540 of human SLCO3A1 (NP_037404.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | A-549, Mouse kidney, Mouse thymus, Mouse lung, Rat brain, Rat thymus |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 440-540 of human SLCO3A1 (NP_037404.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | FLGC DTGP VAGV TVPY GNST APGS ALDP YSPC NNNC ECQT DSFT PVCG ADGI TYLS ACFA GCNS TNLT GCAC LTTV PAEN ATVV PGKC PSPG CQEA FLTF L |
| 遺伝子ID: | 28232 |
| Uniprot: | Q9UIG8 |
| セルラーロケーション: | Cell membrane, Multi-pass membrane protein |
| 計算された分子量: | 46kDa/62kDa/74kDa/76kDa |
| 観察された分子量: | 76kDa |
| 同義語: | SLCO3A1, OATP-D, OATP-RP3, OATP3A1, OATPD, OATPRP3, SLC21A11 |
| バックグラウンド: |
| UniProt Protein Function: | SLCO3A1: Mediates the Na(+)-independent transport of organic anions such as estrone-3-sulfate (PubMed:10873595). Mediates transport of prostaglandins (PG) E1 and E2, thyroxine (T4), deltorphin II, BQ-123 and vasopressin, but not DPDPE (a derivative of enkephalin lacking an N-terminal tyrosine residue), estrone-3- sulfate, taurocholate, digoxin nor DHEAS (PubMed:16971491). Belongs to the organo anion transporter (TC 2.A.60) family. 4 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Transporter, SLC family; Transporter; Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 15q26 Cellular Component: plasma membrane; integral to membrane Molecular Function:transporter activity Biological Process: sodium-independent organic anion transport; transmembrane transport |
| UniProt Code: | Q9UIG8 |
| NCBI GenInfo Identifier: | 12003094 |
| NCBI Gene ID: | 28232 |
| NCBI Accession: | AAG43446.1 |
| UniProt Secondary Accession: | Q9UIG8,Q9BW73, Q9GZV2, A8K4A7, B3KPY5, B3KUR7, C6G486 |
| UniProt Related Accession: | Q9UIG8 |
| Molecular Weight: | 76,553 Da |
| NCBI Full Name: | PGE1 transporter |
| NCBI Synonym Full Names: | solute carrier organic anion transporter family, member 3A1 |
| NCBI Official Symbol: | SLCO3A1 |
| NCBI Official Synonym Symbols: | OATPD; OATP-D; OATP3A1; SLC21A11 |
| NCBI Protein Information: | solute carrier organic anion transporter family member 3A1; OATPRP3; OATP-RP3; PGE1 transporter; solute carrier family 21 member 11; organic anion-transporting polypeptide D; sodium-independent organic anion transporter D; organic anion transporter polypeptide-related protein 3; solute carrier family 21 (organic anion transporter), member 11 |
| UniProt Protein Name: | Solute carrier organic anion transporter family member 3A1 |
| UniProt Synonym Protein Names: | Organic anion transporter polypeptide-related protein 3; OATP-RP3; OATPRP3; Organic anion-transporting polypeptide D; OATP-D; PGE1 transporter; Sodium-independent organic anion transporter D; Solute carrier family 21 member 11 |
| UniProt Gene Name: | SLCO3A1 |
| UniProt Entry Name: | SO3A1_HUMAN |
 | Western blot analysis of extracts of various cell lines, using SLCO3A1 antibody (CAB14276) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s. |
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