Anti-SLC9A3R2 Antibody (CAB17591)
- SKU:
- CAB17591
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
Frequently bought together:
Description
抗体名: | Anti-SLC9A3R2 Antibody |
抗体コード: | CAB17591 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 180-300 of human SLC9A3R2 (NP_001123484). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human |
ポジティブサンプル: | HeLa |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 180-300 of human SLC9A3R2 (NP_001123484). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | DPGS PAAR SGLR AQDR LIEV NGQN VEGL RHAE VVAS IKAR EDEA RLLV VDPE TDEH FKRL RVTP TEEH VEGP LPSP VTNG TSPA QLNG GSAC SSRS DLPG SDKD TEDG SAWK QDPF QESG L |
遺伝子ID: | 9351 |
Uniprot: | Q15599 |
セルラーロケーション: | |
計算された分子量: | |
観察された分子量: | 50kDa |
同義語: | E3KARP, NHE3RF2, NHERF-2, NHERF2, OCTS2, SIP-1, SIP1, TKA-1, SLC9A3R2 |
バックグラウンド: | This gene encodes a member of the NHERF family of PDZ scaffolding proteins. These proteins mediate many cellular processes by binding to and regulating the membrane expression and protein-protein interactions of membrane receptors and transport proteins. The encoded protein plays a role in intestinal sodium absorption by regulating the activity of the sodium/hydrogen exchanger 3, and may also regulate the cystic fibrosis transmembrane regulator (CFTR) ion channel. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011] |
UniProt Protein Function: | Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3 (PubMed:18829453). May also act as scaffold protein in the nucleus. |
NCBI Summary: | This gene encodes a member of the NHERF family of PDZ scaffolding proteins. These proteins mediate many cellular processes by binding to and regulating the membrane expression and protein-protein interactions of membrane receptors and transport proteins. The encoded protein plays a role in intestinal sodium absorption by regulating the activity of the sodium/hydrogen exchanger 3, and may also regulate the cystic fibrosis transmembrane regulator (CFTR) ion channel. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011] |
UniProt Code: | Q15599 |
NCBI GenInfo Identifier: | 194018553 |
NCBI Gene ID: | 9351 |
NCBI Accession: | NP_001123484.1 |
UniProt Secondary Accession: | Q15599,O00272, O00556, Q3KQY7, D3DU84, D3DU85, H3BSV6 |
UniProt Related Accession: | Q15599 |
Molecular Weight: | 24,718 Da |
NCBI Full Name: | Na(+)/H(+) exchange regulatory cofactor NHE-RF2 isoform a |
NCBI Synonym Full Names: | SLC9A3 regulator 2 |
NCBI Official Symbol: | SLC9A3R2 |
NCBI Official Synonym Symbols: | SIP1; OCTS2; SIP-1; TKA-1; E3KARP; NHERF2; NHE3RF2; NHERF-2 |
NCBI Protein Information: | Na(+)/H(+) exchange regulatory cofactor NHE-RF2 |
UniProt Protein Name: | Na(+)/H(+) exchange regulatory cofactor NHE-RF2 |
UniProt Synonym Protein Names: | NHE3 kinase A regulatory protein E3KARP; SRY-interacting protein 1; SIP-1; Sodium-hydrogen exchanger regulatory factor 2; Solute carrier family 9 isoform A3 regulatory factor 2; Tyrosine kinase activator protein 1; TKA-1 |
UniProt Gene Name: | SLC9A3R2 |