Anti-SLC44A4 Antibody (CAB10435)
- SKU:
- CAB10435
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-SLC44A4 Antibody |
| 抗体コード: | CAB10435 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 65-215 of human SLC44A4 (NP_079533.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | HT-29, K-562, Mouse kidney, Mouse lung |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 65-215 of human SLC44A4 (NP_079533.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | LYPR NSTG AYCG MGEN KDKP YLLY FNIF SCIL SSNI ISVA ENGL QCPT PQVC VSSC PEDP WTVG KNEF SQTV GEVF YTKN RNFC LPGV PWNM TVIT SLQQ ELCP SFLL PSAP ALGR CFPW TNVT PPAL PGIT NDTT IQQG ISGL IDSL NAR |
| 遺伝子ID: | 80736 |
| Uniprot: | Q53GD3 |
| セルラーロケーション: | Membrane, Multi-pass membrane protein |
| 計算された分子量: | 32kDa/70kDa/74kDa/79kDa |
| 観察された分子量: | 79kDa |
| 同義語: | SLC44A4, C6orf29, CTL4, NG22, TPPT |
| バックグラウンド: | The protein encoded by this gene may be a sodium-dependent transmembrane transport protein involved in the uptake of choline by cholinergic neurons. Defects in this gene can cause sialidosis, a lysosomal storage disease. Three transcript variants encoding different isoforms have been found for this gene. |
| UniProt Protein Function: | SLC44A4: An interstitial deletion causing the fusion of exon 10 of CTL4 with the 3'-UTR of NEU has been detected in two patients affected by sialidosis. Belongs to the CTL (choline transporter-like) family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family Chromosomal Location of Human Ortholog: 6p21.33 Cellular Component: plasma membrane Molecular Function:choline transmembrane transporter activity Biological Process: acetylcholine biosynthetic process; phosphatidylcholine biosynthetic process; positive regulation of cell growth; transmembrane transport |
| NCBI Summary: | The protein encoded by this gene may be a sodium-dependent transmembrane transport protein involved in the uptake of choline by cholinergic neurons. Defects in this gene can cause sialidosis, a lysosomal storage disease. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010] |
| UniProt Code: | Q53GD3 |
| NCBI GenInfo Identifier: | 311033368 |
| NCBI Gene ID: | 80736 |
| NCBI Accession: | Q53GD3.2 |
| UniProt Secondary Accession: | Q53GD3,Q5JP84, Q5JQ93, Q658S8, Q6UX89, Q8TEW4, A2BED3 B0UXX8, B0UZY8, B4DU94, B4DWM2, E9PEK7, |
| UniProt Related Accession: | Q53GD3 |
| Molecular Weight: | 79kDa |
| NCBI Full Name: | Choline transporter-like protein 4 |
| NCBI Synonym Full Names: | solute carrier family 44 member 4 |
| NCBI Official Symbol: | SLC44A4 |
| NCBI Official Synonym Symbols: | CTL4; NG22; TPPT; C6orf29 |
| NCBI Protein Information: | choline transporter-like protein 4 |
| UniProt Protein Name: | Choline transporter-like protein 4 |
| UniProt Synonym Protein Names: | Solute carrier family 44 member 4 |
| Protein Family: | Choline transporter-like protein |
| UniProt Gene Name: | SLC44A4 |
 | Western blot analysis of extracts of various cell lines, using SLC44A4 antibody (CAB10435) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
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