Anti-SLC28A3 Antibody (CAB10320)
- SKU:
- CAB10320
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-SLC28A3 Antibody |
| 抗体コード: | CAB10320 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 612-691 of human SLC28A3 (NP_071410.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | HepG2, 293T |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 612-691 of human SLC28A3 (NP_071410.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | LSST PVDI NCHH VLEN AFNS TFPG NTTK VIAC CQSL LSST VAKG PGEV IPGG NHSL YSLK GCCT LLNP STFN CNGI SNTF |
| 遺伝子ID: | 64078 |
| Uniprot: | Q9HAS3 |
| セルラーロケーション: | Cell membrane, Endoplasmic reticulum membrane, Multi-pass membrane protein |
| 計算された分子量: | 69kDa/76kDa |
| 観察された分子量: | 77kDa |
| 同義語: | SLC28A3, CNT3 |
| バックグラウンド: |
| UniProt Protein Function: | SLC28A3: Sodium-dependent, pyrimidine- and purine-selective. Involved in the homeostasis of endogenous nucleosides. Exhibits the transport characteristics of the nucleoside transport system cib or N3 subtype (N3/cib) (with marked transport of both thymidine and inosine). Employs a 2:1 sodium/nucleoside ratio. Also able to transport gemcitabine, 3'-azido-3'-deoxythymidine (AZT), ribavirin and 3-deazauridine. Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family. |
| UniProt Protein Details: | Protein type:Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family Chromosomal Location of Human Ortholog: 9q21.32-q21.33 Cellular Component: integral to plasma membrane; plasma membrane Molecular Function:nucleoside:sodium symporter activity; purine-specific nucleoside:sodium symporter activity; pyrimidine- and adenine-specific:sodium symporter activity Biological Process: pyrimidine nucleoside transport |
| NCBI Summary: | Nucleoside transporters, such as SLC28A3, regulate multiple cellular processes, including neurotransmission, vascular tone, adenosine concentration in the vicinity of cell surface receptors, and transport and metabolism of nucleoside drugs. SLC28A3 shows broad specificity for pyrimidine and purine nucleosides (Ritzel et al., 2001 [PubMed 11032837]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q9HAS3 |
| NCBI GenInfo Identifier: | 74752767 |
| NCBI Gene ID: | 64078 |
| NCBI Accession: | Q9HAS3.1 |
| UniProt Secondary Accession: | Q9HAS3,A8K9Y4, B1AML0, B2RA51, B4E2S8, F5GYE3, |
| UniProt Related Accession: | Q9HAS3 |
| Molecular Weight: | 77kDa |
| NCBI Full Name: | Solute carrier family 28 member 3 |
| NCBI Synonym Full Names: | solute carrier family 28 member 3 |
| NCBI Official Symbol: | SLC28A3 |
| NCBI Official Synonym Symbols: | CNT3 |
| NCBI Protein Information: | solute carrier family 28 member 3 |
| UniProt Protein Name: | Solute carrier family 28 member 3 |
| UniProt Synonym Protein Names: | Concentrative Na(+)-nucleoside cotransporter 3; CNT 3; hCNT3 |
| Protein Family: | Solute carrier family |
| UniProt Gene Name: | SLC28A3 |
 | Western blot analysis of extracts of various cell lines, using SLC28A3 antibody (CAB10320) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s. |
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