Anti-SLC1A5 Antibody (CAB12676)

(No reviews yet) Write a Review
お見積り依頼
SKU:
CAB12676
Product type:
Antibody
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction
€0.00
Frequently bought together:

Description

system_update_altデータシートsystem_update_alt安全性データシート
抗体名:Anti-SLC1A5 Antibody
抗体コード:CAB12676
抗体サイズ:20uL, 50uL, 100uL
申し込み:WB
反応性:Rat
宿主種:Rabbit
免疫原:Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human SLC1A5 (NP_005619.1).
申し込み:WB
推奨希釈:WB 1:500 - 1:2000
反応性:Rat
ポジティブサンプル:Rat lung
免疫原:Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human SLC1A5 (NP_005619.1).
精製方法:Affinity purification
ストレージバッファ:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
アイソタイプ:IgG
順序:MVAD PPRD SKGL AAAE PTAN GGLA LASI EDQG AAAG GYCG SRDQ VRRC LRAN LLVL LTVV AVVA GVAL GLGV SGAG GALA LGPE RLSA FVFP GELL LRLL
遺伝子ID:6510
Uniprot:Q15758
セルラーロケーション:Cell membrane, Melanosome, Multi-pass membrane protein
計算された分子量:33kDa/36kDa/56kDa
観察された分子量:57kDa
同義語:SLC1A5, AAAT, ASCT2, ATBO, M7V1, M7VS1, R16, RDRC
バックグラウンド:
UniProt Protein Function:SLC1A5: Has a broad substrate specificity, a preference for zwitterionic amino acids, and a sodium-dependence. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated amino acids, anionic amino acids, and cationic amino acids. Act as a cell surface receptor for feline endogenous virus RD114, baboon M7 endogenous virus and type D simian retroviruses. Placenta, lung, skeletal muscle, kidney, pancreas, and intestine. Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family. SLC1A5 subfamily. 1 isoforms of the human protein are produced by alternative initiation.
UniProt Protein Details:

Protein type:Transporter; Transporter, SLC family; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 19q13.3

Cellular Component: Golgi apparatus; integral to plasma membrane; membrane; plasma membrane

Molecular Function:amino acid transmembrane transporter activity; L-glutamine transmembrane transporter activity; neutral amino acid transmembrane transporter activity; protein binding; receptor activity

Biological Process: amino acid transport; glutamine transport; neutral amino acid transport

NCBI Summary:The SLC1A5 gene encodes a sodium-dependent neutral amino acid transporter that can act as a receptor for RD114/type D retrovirus (Larriba et al., 2001 [PubMed 11781704]).[supplied by OMIM, Jan 2011]
UniProt Code:Q15758
NCBI GenInfo Identifier:21542389
NCBI Gene ID:6510
NCBI Accession:Q15758.2
UniProt Secondary Accession:Q15758,O95720, Q96RL9, Q9BWQ3, Q9UNP2, A8K9H5, B4DR77 B4DWS4, B7ZB81, D0EYG6, E9PC01,
UniProt Related Accession:Q15758
Molecular Weight:33,710 Da
NCBI Full Name:Neutral amino acid transporter B(0)
NCBI Synonym Full Names:solute carrier family 1 member 5
NCBI Official Symbol:SLC1A5  
NCBI Official Synonym Symbols:R16; AAAT; ATBO; M7V1; RDRC; ASCT2; M7VS1  
NCBI Protein Information:neutral amino acid transporter B(0)
UniProt Protein Name:Neutral amino acid transporter B(0)
UniProt Synonym Protein Names:Baboon M7 virus receptor; RD114/simian type D retrovirus receptor; Sodium-dependent neutral amino acid transporter type 2; Solute carrier family 1 member 5
Protein Family:Neutral amino acid transporter
UniProt Gene Name:SLC1A5  
UniProt Entry Name:AAAT_HUMAN
Anti-SLC1A5 Antibody (CAB12676)Western blot analysis of extracts of rat lung, using SLC1A5 antibody (CAB12676) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
View AllClose

View AllClose