Anti-SKIV2L2 Antibody (CAB5576)
- SKU:
- CAB5576
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
| 抗体名: | Anti-SKIV2L2 Antibody |
| 抗体コード: | CAB5576 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC IP |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-304 of human SKIV2L2 (NP_056175.3). |
| 申し込み: | WB IHC IP |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IP 1:50 - 1:200 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | HeLa, 22RV1, 293T, U-87MG, Mouse testis, Mouse spleen |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-304 of human SKIV2L2 (NP_056175.3). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MADA FGDE LFSV FEGD STTA AGTK KDKE KDKG KWKG PPGS ADKA GKRF DGKL QSES TNNG KNKR DVDF EGTD EPIF GKKP RIEE SITE DLSL ADLM PRVK VQSV ETVE GCTH EVAL PAEE DYLP LKPR VGKA AKEY PFIL DAFQ REAI QCVD NNQS VLVS AHTS AGKT VCAE YAIA LALR EKQR VIFT SPIK ALSN QKYR EMYE EFQD VGLM TGDV TINP TASC LVMT TEIL RSML YRGS EVMR EVAW VIFD EIHY MRDS ERGV VWEE TIIL LPDN VHYV FLSA TIPN ARQF AEWI CHLH KQPC |
| 遺伝子ID: | 23517 |
| Uniprot: | P42285 |
| セルラーロケーション: | Nucleus, nucleolus, nucleoplasm |
| 計算された分子量: | 117kDa |
| 観察された分子量: | 123kDa |
| 同義語: | SKIV2L2, Dob1, KIAA0052, Mtr4, fSAP118 |
| バックグラウンド: |
| UniProt Protein Function: | SKIV2L2: May be involved in pre-mRNA splicing. Associated with the RNA exosome complex and involved in the 3'processing of the 7S pre-RNA to the mature 5.8S rRNA. Belongs to the helicase family. SKI2 subfamily. |
| UniProt Protein Details: | Protein type:Spliceosome; EC 3.6.4.13; Nucleolus; DNA-binding; Helicase Chromosomal Location of Human Ortholog: 5q11.2 Cellular Component: nucleoplasm; nucleolus; exosome (RNase complex); nucleus Molecular Function:protein binding; helicase activity; ATP binding Biological Process: nuclear mRNA splicing, via spliceosome; maturation of 5.8S rRNA |
| UniProt Code: | P42285 |
| NCBI GenInfo Identifier: | 71153172 |
| NCBI Gene ID: | 23517 |
| NCBI Accession: | P42285.3 |
| UniProt Secondary Accession: | P42285,Q2M386, Q6MZZ8, Q6P170, Q8N5R0, Q8TAG2, |
| UniProt Related Accession: | P42285 |
| Molecular Weight: | 1042 |
| NCBI Full Name: | Superkiller viralicidic activity 2-like 2 |
| NCBI Synonym Full Names: | superkiller viralicidic activity 2-like 2 (S. cerevisiae) |
| NCBI Official Symbol: | SKIV2L2 |
| NCBI Official Synonym Symbols: | Dob1; Mtr4; fSAP118; KIAA0052 |
| NCBI Protein Information: | superkiller viralicidic activity 2-like 2; TRAMP-like complex helicase; ATP-dependent helicase SKIV2L2; ATP-dependent RNA helicase SKIV2L2; functional spliceosome-associated protein 118 |
| UniProt Protein Name: | Superkiller viralicidic activity 2-like 2 |
| UniProt Synonym Protein Names: | ATP-dependent RNA helicase SKIV2L2; TRAMP-like complex helicase |
| Protein Family: | ATP-dependent RNA helicase |
| UniProt Gene Name: | SKIV2L2 |
| UniProt Entry Name: | SK2L2_HUMAN |
 | Western blot analysis of extracts of various cell lines, using SKIV2L2 antibody (CAB5576) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 60s. |
 | Immunohistochemistry of paraffin-embedded human breast cancer using SKIV2L2 antibody (CAB5576) at dilution of 1:100 (40x lens). |
 | Immunohistochemistry of paraffin-embedded mouse testis using SKIV2L2 antibody (CAB5576) at dilution of 1:100 (40x lens). |
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