| UniProt Protein Function: | Plays an important role in the final stage of carbohydrate digestion. Isomaltase activity is specific for both alpha-1,4- and alpha-1,6-oligosaccharides. |
| NCBI Summary: | This gene encodes a sucrase-isomaltase enzyme that is expressed in the intestinal brush border. The encoded protein is synthesized as a precursor protein that is cleaved by pancreatic proteases into two enzymatic subunits sucrase and isomaltase. These two subunits heterodimerize to form the sucrose-isomaltase complex. This complex is essential for the digestion of dietary carbohydrates including starch, sucrose and isomaltose. Mutations in this gene are the cause of congenital sucrase-isomaltase deficiency.[provided by RefSeq, Apr 2010] |
| UniProt Code: | P14410 |
| NCBI GenInfo Identifier: | 157364974 |
| NCBI Gene ID: | 6476 |
| NCBI Accession: | NP_001032 |
| UniProt Related Accession: | P14410 |
| Molecular Weight: | 209kDa |
| NCBI Full Name: | sucrase-isomaltase, intestinal |
| NCBI Synonym Full Names: | sucrase-isomaltase |
| NCBI Official Symbol: | SI |
| NCBI Protein Information: | sucrase-isomaltase, intestinal |
| UniProt Protein Name: | Sucrase-isomaltase, intestinal |
| Protein Family: | Sialin |
| UniProt Gene Name: | SI |
