Anti-SH2B1 Antibody (CAB5564)
- SKU:
- CAB5564
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-SH2B1 Antibody |
抗体コード: | CAB5564 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | IHC IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 360-520 of human SH2B1 (NP_056318.2). |
申し込み: | IHC IF |
推奨希釈: | IHC 1:50 - 1:200 IF 1:20 - 1:50 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 360-520 of human SH2B1 (NP_056318.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | DAQH VKAW VSDI QECL SPGP CPAT SPRP MTLP LAPG TSFL TREN TDSL ELSC LNHS ESLP SQDL LLGP SESN DRLS QGAY GGLS DRPS ASIS PSSA SIAA SHFD SMEL LPPE LPPR IPIE EGPP TGTV HPLS APYP PLDT PETA TGSF LFQG EPEG GEGD Q |
遺伝子ID: | 25970 |
Uniprot: | Q9NRF2 |
セルラーロケーション: | Cytoplasm, Membrane, Nucleus |
計算された分子量: | 70kDa/72kDa/79kDa |
観察された分子量: |
同義語: | SH2B1, PSM, SH2B |
バックグラウンド: | This gene encodes a member of the SH2-domain containing mediators family. The encoded protein mediates activation of various kinases and may function in cytokine and growth factor receptor signaling and cellular transformation. Alternatively spliced transcript variants have been described. |
UniProt Protein Function: | SH2-B-beta: an adaptor protein that specifically activates JAK2 and serve as adapter proteins for JAK1, -2 and -3. YXXL motifs in SH2-Bbeta are phosphorylated by JAK2, JAK1, and platelet-derived growth factor receptor and are required for membrane ruffling. |
UniProt Protein Details: | Protein type:Adaptor/scaffold Chromosomal Location of Human Ortholog: 16p11.2 Cellular Component: cytosol Molecular Function:protein binding Biological Process: blood coagulation |
NCBI Summary: | This gene encodes a member of the SH2-domain containing mediators family. The encoded protein mediates activation of various kinases and may function in cytokine and growth factor receptor signaling and cellular transformation. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2009] |
UniProt Code: | Q9NRF2 |
NCBI GenInfo Identifier: | 313104186 |
NCBI Gene ID: | 25970 |
NCBI Accession: | Q9NRF2.3 |
UniProt Secondary Accession: | Q9NRF2,Q96FK3, Q96SX3, Q9NRF1, Q9NRF3, Q9P2P7, Q9Y3Y3 A8K2R7, |
UniProt Related Accession: | Q9NRF2 |
Molecular Weight: | 72,188 Da |
NCBI Full Name: | SH2B adapter protein 1 |
NCBI Synonym Full Names: | SH2B adaptor protein 1 |
NCBI Official Symbol: | SH2B1 |
NCBI Official Synonym Symbols: | PSM; SH2B |
NCBI Protein Information: | SH2B adapter protein 1 |
UniProt Protein Name: | SH2B adapter protein 1 |
UniProt Synonym Protein Names: | Pro-rich, PH and SH2 domain-containing signaling mediator; PSM; SH2 domain-containing protein 1B |
Protein Family: | SH2B adapter protein |
UniProt Gene Name: | SH2B1 |
UniProt Entry Name: | SH2B1_HUMAN |
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