UniProt Protein Function: | Plays a role as an alternative splicing regulator. Regulate its own expression at the level of RNA processing. Also regulates the splicing of fibronectin and CD45 genes. May act, at least in part, by interaction with other R/S-containing splicing factors. Represses the splicing of MAPT/Tau exon 10. |
NCBI Summary: | This gene encodes a human homolog of Drosophila splicing regulatory protein. This gene autoregulates its expression by control of splicing of its first two introns. In addition, it also regulates the splicing of fibronectin and CD45 genes. Two transcript variants encoding different isoforms have been identified. [provided by RefSeq, May 2012] |
UniProt Code: | Q12872 |
NCBI GenInfo Identifier: | 292495067 |
NCBI Gene ID: | 6433 |
NCBI Accession: | Q12872.3 |
UniProt Secondary Accession: | Q12872,Q6PJF7, B2RN45, B7ZM97, F5H6B8, |
UniProt Related Accession: | Q12872 |
Molecular Weight: | 110,012 Da |
NCBI Full Name: | Splicing factor, suppressor of white-apricot homolog |
NCBI Synonym Full Names: | splicing factor SWAP homolog |
NCBI Official Symbol: | SFSWAP |
NCBI Official Synonym Symbols: | SWAP; SFRS8 |
NCBI Protein Information: | splicing factor, suppressor of white-apricot homolog |
UniProt Protein Name: | Splicing factor, suppressor of white-apricot homolog |
UniProt Synonym Protein Names: | Splicing factor, arginine/serine-rich 8; Suppressor of white apricot protein homolog |
Protein Family: | Splicing factor |
UniProt Gene Name: | SFSWAP |
UniProt Entry Name: | SFSWA_HUMAN |