Anti-SERPINB4 Antibody (CAB15316)
- SKU:
- CAB15316
- Product type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-SERPINB4 Antibody |
| 抗体コード: | CAB15316 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human SERPINB4 (NP_002965.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:200 - 1:2000 |
| 反応性: | Mouse, Rat |
| ポジティブサンプル: |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human SERPINB4 (NP_002965.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | RTMG MVNI FNGD ADLS GMTW SHGL SVSK VLHK AFVE VTEE GVEA AAAT AVVV VELS SPST NEEF CCNH PFLF FIRQ NKTN SILF YGRF SSP |
| 遺伝子ID: | 6318 |
| Uniprot: | P48594 |
| セルラーロケーション: | Cytoplasm |
| 計算された分子量: | 44kDa |
| 観察された分子量: | Refer to figures |
| 同義語: | SERPINB4, LEUPIN, PI11, SCCA-2, SCCA1, SCCA2, serpin B4 |
| バックグラウンド: | The protein encoded by this gene is a member of the serpin family of serine protease inhibitors. The encoded protein is highly expressed in many tumor cells and can inactivate granzyme M, an enzyme that kills tumor cells. This protein, along with serpin B3, can be processed into smaller fragments that aggregate to form an autoantigen in psoriasis, probably by causing chronic inflammation. |
| UniProt Protein Function: | SERPINB4: May act as a protease inhibitor to modulate the host immune response against tumor cells. Belongs to the serpin family. Ov-serpin subfamily. |
| UniProt Protein Details: | Protein type:Inhibitor Chromosomal Location of Human Ortholog: 18q21.3 Cellular Component: extracellular space; intracellular Molecular Function:enzyme binding; protease binding; serine-type endopeptidase inhibitor activity Biological Process: negative regulation of peptidase activity; protection from natural killer cell mediated cytotoxicity |
| UniProt Code: | P48594 |
| NCBI GenInfo Identifier: | 1710877 |
| NCBI Gene ID: | 6318 |
| NCBI Accession: | P48594.2 |
| UniProt Secondary Accession: | P48594,A8K847, |
| UniProt Related Accession: | P48594 |
| Molecular Weight: | 44,854 Da |
| NCBI Full Name: | Serpin B4 |
| NCBI Synonym Full Names: | serpin family B member 4 |
| NCBI Official Symbol: | SERPINB4 |
| NCBI Official Synonym Symbols: | PI11; SCCA1; SCCA2; LEUPIN; SCCA-2 |
| NCBI Protein Information: | serpin B4 |
| UniProt Protein Name: | Serpin B4 |
| UniProt Synonym Protein Names: | Leupin; Peptidase inhibitor 11; PI-11; Squamous cell carcinoma antigen 2; SCCA-2 |
| Protein Family: | Serpin |
| UniProt Gene Name: | SERPINB4 |
| UniProt Entry Name: | SPB4_HUMAN |
View AllClose