Anti-Septin-9 Antibody (CAB8657)
- SKU:
- CAB8657
- Product type:
- Antibody
- Application:
- WB
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Cycle
Frequently bought together:
Description
| 抗体名: | Anti-Septin-9 Antibody |
| 抗体コード: | CAB8657 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IF |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human SEPT9 (NP_001106964.1). |
| 申し込み: | WB IF |
| 推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | Jurkat, HeLa, 293T, U-87MG |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human SEPT9 (NP_001106964.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MEPP ASKV PEVP TAPA TDAA PKRV EIQM PKPA EAPT APSP AQTL ENSE PAPV SQLQ SRLE PKPQ PPVA EATP RSQE ATEA APSC VGDM ADTP RDAG LKQA PASR NEKA PV |
| 遺伝子ID: | 10801 |
| Uniprot: | Q9UHD8 |
| セルラーロケーション: | Cytoplasm, cytoskeleton |
| 計算された分子量: | 38kDa/41kDa/47kDa/52kDa/63kDa/64kDa/65kDa |
| 観察された分子量: | 75kDa |
| 同義語: | SEPT9, AF17q25, MSF, MSF1, NAPB, PNUTL4, SINT1, SeptD1, septin-9 |
| バックグラウンド: | This gene is a member of the septin family involved in cytokinesis and cell cycle control. This gene is a candidate for the ovarian tumor suppressor gene. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been described. |
| UniProt Protein Function: | Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri. |
| NCBI Summary: | This gene is a member of the septin family involved in cytokinesis and cell cycle control. This gene is a candidate for the ovarian tumor suppressor gene. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Mar 2009] |
| UniProt Code: | Q9UHD8 |
| NCBI GenInfo Identifier: | 18203688 |
| NCBI Gene ID: | 10801 |
| NCBI Accession: | AAH21192.1 |
| UniProt Secondary Accession: | Q9UHD8,Q96QF3, Q96QF4, Q96QF5, Q9HA04, Q9UG40, A8K2V3 B3KPM0, B4DTL9, B4E0N2, B4E274, B7Z654, |
| UniProt Related Accession: | Q9UHD8 |
| Molecular Weight: | 41,187 Da |
| NCBI Full Name: | Septin 9 |
| NCBI Synonym Full Names: | septin 9 |
| NCBI Official Symbol: | SEPT9 |
| NCBI Official Synonym Symbols: | MSF; MSF1; NAPB; SINT1; PNUTL4; SeptD1; AF17q25 |
| NCBI Protein Information: | septin-9 |
| UniProt Protein Name: | Septin-9 |
| UniProt Synonym Protein Names: | MLL septin-like fusion protein MSF-A; MLL septin-like fusion protein; Ovarian/Breast septin; Ov/Br septin; Septin D1 |
| UniProt Gene Name: | SEPT9 |
| UniProt Entry Name: | SEPT9_HUMAN |
 | Western blot analysis of extracts of various cell lines, using SEPT9 antibody (CAB8657) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
 | Confocal immunofluorescence analysis of U2OS cells using SEPT9 Polyclonal Antibody (CAB8657) at dilution of 1:100. Blue: DAPI for nuclear staining. |