Anti-SEPT8 Antibody (CAB15011)
- SKU:
- CAB15011
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-SEPT8 Antibody |
抗体コード: | CAB15011 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 348-427 of human SEPT8 (NP_001287728.1). |
申し込み: | WB IHC IF |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | U-251MG, HeLa, LO2, Mouse heart, Mouse kidney, Rat brain |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 348-427 of human SEPT8 (NP_001287728.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | NKVK ETEL ELKE KERE LHEK FEHL KRVH QEEK RKVE EKRR ELEE ETNA FNRR KAAV EALQ SQAL HATS QQPL RKDK DKKN |
遺伝子ID: | 23176 |
Uniprot: | Q92599 |
セルラーロケーション: | Cytoplasm, cytoskeleton |
計算された分子量: | 43kDa/49kDa/51kDa/55kDa |
観察された分子量: | 54kDa |
同義語: | SEPT8, 42980, SEP2, septin-8 |
バックグラウンド: | This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
UniProt Protein Function: | SEPT8: Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). May play a role in platelet secretion. Belongs to the septin family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Cytoskeletal; Hydrolase Chromosomal Location of Human Ortholog: 5q31 Cellular Component: cytoskeleton; cytoplasm Molecular Function:protein binding; GTP binding Biological Process: cell cycle |
NCBI Summary: | This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014] |
UniProt Code: | Q92599 |
NCBI GenInfo Identifier: | 45645200 |
NCBI Gene ID: | 23176 |
NCBI Accession: | Q92599.4 |
UniProt Related Accession: | Q92599 |
Molecular Weight: | ~ 55kDa |
NCBI Full Name: | Septin-8 |
NCBI Synonym Full Names: | septin 8 |
NCBI Official Symbol: | SEPTIN8 |
NCBI Official Synonym Symbols: | SEP2; SEPT8 |
NCBI Protein Information: | septin-8 |
UniProt Protein Name: | Septin-8 |
UniProt Gene Name: | SEPT8 |
UniProt Entry Name: | SEPT8_HUMAN |
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