Anti-SEPT11 Antibody (CAB12189)
- SKU:
- CAB12189
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Frequently bought together:
Description
| 抗体名: | Anti-SEPT11 Antibody |
| 抗体コード: | CAB12189 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human SEPT11 (NP_060713.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | HT-29, 293T, A-431, HeLa, Mouse liver, Rat brain, Rat testis |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human SEPT11 (NP_060713.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MAVA VGRP SNEE LRNL SLSG HVGF DSLP DQLV NKST SQGF CFNI LCVG ETGI GKST LMDT LFNT KFES DPAT HNEP GVRL KARS YELQ ESNV RLKL TIVD TVGF GDQI NKDD SYKP IVEY |
| 遺伝子ID: | 55752 |
| Uniprot: | Q9NVA2 |
| セルラーロケーション: | Cell junction, Cell projection, Cytoplasm, axon, cytoskeleton, dendritic spine, synapse |
| 計算された分子量: | 49kDa/50kDa |
| 観察された分子量: | 49kDa |
| 同義語: | SEPT11, septin-11 |
| バックグラウンド: |
| UniProt Protein Function: | SEPT11: Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). May play a role in the cytoarchitecture of neurons, including dendritic arborization and dendritic spines, and in GABAergic synaptic connectivity. During Listeria monocytogenes infection, not required for the bacterial entry process, but restricts its efficacy. A chromosomal aberration involving SEPT11 may be a cause of chronic neutrophilic leukemia. Translocation t(4;11)(q21;q23) with MLL/HRX. Belongs to the septin family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Cell cycle regulation; Cytoskeletal; Hydrolase; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 4q21.1 Cellular Component: stress fiber Molecular Function:protein binding Biological Process: protein heterooligomerization |
| NCBI Summary: | SEPT11 belongs to the conserved septin family of filament-forming cytoskeletal GTPases that are involved in a variety of cellular functions including cytokinesis and vesicle trafficking (Hanai et al., 2004 [PubMed 15196925]; Nagata et al., 2004 [PubMed 15485874]).[supplied by OMIM, Jul 2009] |
| UniProt Code: | Q9NVA2 |
| NCBI GenInfo Identifier: | 50401687 |
| NCBI Gene ID: | 55752 |
| NCBI Accession: | Q9NVA2.3 |
| UniProt Secondary Accession: | Q9NVA2,Q4W5G1, Q7L4N1, Q96SP1, Q9UFY9, B7Z7Z6, E9KL32 |
| UniProt Related Accession: | Q9NVA2 |
| Molecular Weight: | 49kDa |
| NCBI Full Name: | Septin-11 |
| NCBI Synonym Full Names: | septin 11 |
| NCBI Official Symbol: | SEPT11 |
| NCBI Protein Information: | septin-11 |
| UniProt Protein Name: | Septin-11 |
| UniProt Gene Name: | SEPT11 |
 | Western blot analysis of extracts of various cell lines, using SEPT11 antibody (CAB12189) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |