Anti-SEMG2 Antibody (CAB12878)
- SKU:
- CAB12878
- Product type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-SEMG2 Antibody |
| 抗体コード: | CAB12878 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 383-582 of human SEMG2 (NP_002999.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:1000 - 1:2000 |
| 反応性: | Mouse |
| ポジティブサンプル: | Mouse testis |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 383-582 of human SEMG2 (NP_002999.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | HGKS QNQV RIPS QAQE YGHK ENKI SYQS SSTE ERRL NSGE KDVQ KGVS KGSI SIQT EEKI HGKS QNQV TIPS QDQE HGHK ENKM SYQS SSTE ERRL NYGG KSTQ KDVS QSSI SFQI EKLV EGKS QIQT PNPN QDQW SGQN AKGK SGQS ADSK QDLL SHEQ KGRY KQES SESH NIVI TEHE VAQD DHLT QQYN EDRN PIST |
| 遺伝子ID: | 6407 |
| Uniprot: | Q02383 |
| セルラーロケーション: | Secreted |
| 計算された分子量: | 65kDa |
| 観察された分子量: | 66kDa |
| 同義語: | SEMG2, SGII |
| バックグラウンド: | The secreted protein encoded by this gene is involved in the formation of a gel matrix that encases ejaculated spermatozoa. Proteolysis by the prostate-specific antigen (PSA) breaks down the gel matrix and allows the spermatozoa to move more freely. The encoded protein is found in lesser abundance than a similar semenogelin protein. An antibacterial activity has been found for a antimicrobial peptide isolated from this protein. The genes encoding these two semenogelin proteins are found in a cluster on chromosome 20. |
| UniProt Protein Function: | SEMG2: Participates in the formation of a gel matrix (sperm coagulum) entrapping the accessory gland secretions and ejaculated spermatozoa. Belongs to the semenogelin family. |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 20q13.12 Cellular Component: extracellular space; nucleus Molecular Function:metal ion binding; protease binding; protein binding Biological Process: antibacterial humoral response; coagulation; protein heterooligomerization |
| NCBI Summary: | The secreted protein encoded by this gene is involved in the formation of a gel matrix that encases ejaculated spermatozoa. Proteolysis by the prostate-specific antigen (PSA) breaks down the gel matrix and allows the spermatozoa to move more freely. The encoded protein is found in lesser abundance than a similar semenogelin protein. An antibacterial activity has been found for a antimicrobial peptide isolated from this protein. The genes encoding these two semenogelin proteins are found in a cluster on chromosome 20. [provided by RefSeq, Jan 2015] |
| UniProt Code: | Q02383 |
| NCBI GenInfo Identifier: | 401079 |
| NCBI Gene ID: | 6407 |
| NCBI Accession: | Q02383.1 |
| UniProt Secondary Accession: | Q02383,Q53ZU2, Q6X2M5, Q6X2M6, |
| UniProt Related Accession: | Q02383 |
| Molecular Weight: | 65kDa |
| NCBI Full Name: | Semenogelin-2 |
| NCBI Synonym Full Names: | semenogelin II |
| NCBI Official Symbol: | SEMG2 |
| NCBI Official Synonym Symbols: | SGII |
| NCBI Protein Information: | semenogelin-2 |
| UniProt Protein Name: | Semenogelin-2 |
| UniProt Synonym Protein Names: | Semenogelin II; SGII |
| Protein Family: | Semenogelin |
| UniProt Gene Name: | SEMG2 |
 | Western blot analysis of extracts of mouse testis, using SEMG2 antibody (CAB12878) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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