Anti-SEC31A Antibody (CAB9321)
- SKU:
- CAB9321
- Product type:
- Antibody
- Application:
- WB
- Application:
- IF
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-SEC31A Antibody |
抗体コード: | CAB9321 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 300-500 of human SEC31A (NP_055748.2). |
申し込み: | WB |
推奨希釈: | WB 1:1000 - 1:2000 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | Mouse liver, Rat liver |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 300-500 of human SEC31A (NP_055748.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | PTNT QWCF DIQW CPRN PAVL SAAS FDGR ISVY SIMG GSTD GLRQ KQVD KLSS SFGN LDPF GTGQ PLPP LQIP QQTA QHSI VLPL KKPP KWIR RPVG ASFS FGGK LVTF ENVR MPSH QGAE QQQQ QHHV FISQ VVTE KEFL SRSD QLQQ AVQS QGFI NYCQ KKID ASQT EFEK NVWS FLKV NFED DSRG KYLE LLGY RKED L |
遺伝子ID: | 22872 |
Uniprot: | O94979 |
セルラーロケーション: | COPII-coated vesicle membrane, Cytoplasm, Cytoplasmic side, Cytoplasmic vesicle, Endoplasmic reticulum membrane, Peripheral membrane protein |
計算された分子量: | 56kDa/105-134kDa |
観察された分子量: | 165kDa |
同義語: | SEC31A, ABP125, ABP130, HSPC275, HSPC334, SEC31L1 |
バックグラウンド: | The protein encoded by this gene shares similarity with the yeast Sec31 protein, and is a component of the outer layer of the coat protein complex II (COPII). The encoded protein is involved in vesicle budding from the endoplasmic reticulum (ER) and contains multiple WD repeats near the N-terminus and a proline-rich region in the C-terminal half. It associates with the protein encoded by the SEC13 homolog, nuclear pore and COPII coat complex component (SEC13), and is required for ER-Golgi transport. Monoubiquitylation of this protein by CUL3-KLHL12 was found to regulate the size of COPII coats to accommodate unusually shaped cargo. Alternative splicing results in multiple transcript variants encoding different isoforms. |
UniProt Protein Function: | Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER) (PubMed:10788476). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. |
NCBI Summary: | The protein encoded by this gene shares similarity with the yeast Sec31 protein, and is a component of the outer layer of the coat protein complex II (COPII). The encoded protein is involved in vesicle budding from the endoplasmic reticulum (ER) and contains multiple WD repeats near the N-terminus and a proline-rich region in the C-terminal half. It associates with the protein encoded by the SEC13 homolog, nuclear pore and COPII coat complex component (SEC13), and is required for ER-Golgi transport. Monoubiquitylation of this protein by CUL3-KLHL12 was found to regulate the size of COPII coats to accommodate unusually shaped cargo. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015] |
UniProt Code: | O94979 |
NCBI GenInfo Identifier: | 1207836306 |
NCBI Gene ID: | 22872 |
NCBI Accession: | OWK13809.1 |
UniProt Secondary Accession: | O94979,Q17RR5, Q5H9P6, Q5XG74, Q659G7, Q6ZU90, Q7LCX9 Q86TJ0, B4DIW6, B7ZKZ7, B7ZL00, H7C2W3, |
UniProt Related Accession: | O94979 |
Molecular Weight: | 133kDa |
NCBI Full Name: | SEC31A, partial |
NCBI Synonym Full Names: | SEC31 homolog A, COPII coat complex component |
NCBI Official Symbol: | SEC31A |
NCBI Official Synonym Symbols: | ABP125; ABP130; HSPC275; HSPC334; SEC31L1 |
NCBI Protein Information: | protein transport protein Sec31A |
UniProt Protein Name: | Protein transport protein Sec31A |
UniProt Synonym Protein Names: | ABP125; ABP130; SEC31-like protein 1; SEC31-related protein A; Web1-like protein |
Protein Family: | Protein transport protein |
UniProt Gene Name: | SEC31A |
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