Anti-SEC24C Antibody (CAB10797)
- SKU:
- CAB10797
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-SEC24C Antibody |
| 抗体コード: | CAB10797 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 915-1094 of human SEC24C (NP_004913.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human |
| ポジティブサンプル: | HeLa, HT-29, SKOV3 |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 915-1094 of human SEC24C (NP_004913.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | DVLQ PGAE VTTD DRAY VRQL VTSM DVTE TNVF FYPR LLPL TKSP VEST TEPP AVRA SEER LSNG DIYL LENG LNLF LWVG ASVQ QGVV QSLF SVSS FSQI TSGL SVLP VLDN PLSK KVRG LIDS LRAQ RSRY MKLT VVKQ EDKM EMLF KHFL VEDK SLSG GASY VDFL CHMH KEIR QLLS |
| 遺伝子ID: | 9632 |
| Uniprot: | P53992 |
| セルラーロケーション: | Cytoplasm, Endoplasmic reticulum membrane, Golgi apparatus membrane, perinuclear region |
| 計算された分子量: | 38kDa/118kDa |
| 観察された分子量: | 118kDa |
| 同義語: | SEC24C |
| バックグラウンド: | The protein encoded by this gene is a member of the SEC24 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec24p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The product of this gene may play a role in shaping the vesicle, as well as in cargo selection and concentration. Alternatively spliced transcript variants encoding the same protein have been identified. |
| UniProt Protein Function: | SEC24C: Component of the COPII coat, that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the Golgi complex. Interacts with SLC6A4. COPII is composed of at least five proteins: the Sec23/24 complex, the Sec13/31 complex and Sar1. SEC24C is capable of forming heterodimers with SEC24A. Interacts with TMED2 and TMED10. Ubiquitous. Belongs to the SEC23/SEC24 family. SEC24 subfamily. |
| UniProt Protein Details: | Protein type:Motor Chromosomal Location of Human Ortholog: 10q22.2 Cellular Component: cytosol; endoplasmic reticulum membrane Molecular Function:protein binding Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class II; antigen processing and presentation of peptide antigen via MHC class I; COPII coating of Golgi vesicle; ER to Golgi vesicle-mediated transport |
| NCBI Summary: | The protein encoded by this gene is a member of the SEC24 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec24p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The product of this gene may play a role in shaping the vesicle, as well as in cargo selection and concentration. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P53992 |
| NCBI GenInfo Identifier: | 257051070 |
| NCBI Gene ID: | 9632 |
| NCBI Accession: | P53992.3 |
| UniProt Secondary Accession: | P53992,Q8WV25, B4DZT4, |
| UniProt Related Accession: | P53992 |
| Molecular Weight: | 38,181 Da |
| NCBI Full Name: | Protein transport protein Sec24C |
| NCBI Synonym Full Names: | SEC24 homolog C, COPII coat complex component |
| NCBI Official Symbol: | SEC24C |
| NCBI Protein Information: | protein transport protein Sec24C |
| UniProt Protein Name: | Protein transport protein Sec24C |
| UniProt Synonym Protein Names: | SEC24-related protein C |
| Protein Family: | Protein transport protein |
| UniProt Gene Name: | SEC24C |
| UniProt Entry Name: | SC24C_HUMAN |
 | Western blot analysis of extracts of various cell lines, using SEC24C antibody (CAB10797) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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