Anti-Sec23A Antibody (CAB8613)
- SKU:
- CAB8613
- Product type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- CLSD
Frequently bought together:
Description
| 抗体名: | Sec23A Rabbit mAb |
| 抗体コード: | CAB8613 |
| サイズ: | 20uL, 50uL, 100uL |
| 同義語: | CLSD |
| 申し込み: | WB, IHC, IF |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | A synthesized peptide derived from human Sec23AA |
| 申し込み: | WB, IHC, IF |
| 推奨される希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | HepG2 |
| 免疫原: | A synthesized peptide derived from human Sec23AA |
| 精製方法: | Affinity purification |
| 保管所: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 10484 |
| Uniprot: | Q15436 |
| セルラーロケーション: | Golgi apparatus membrane, Peripheral membrane protein, Smooth endoplasmic reticulum membrane |
| 計算された分子量: | 86kDa |
| 観察された分子量: | 85kDa |
| UniProt Protein Function: | SEC23A: Component of the COPII coat, that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the Golgi complex. COPII is composed of at least five proteins: the Sec23/24 complex, the Sec13/31 complex and Sar1. Interacts with SEC23IP. Interacts with HTR4. Interacts with SLC6A4. Interacts with SEC16A. Belongs to the SEC23/SEC24 family. SEC23 subfamily. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 14q21.1 Cellular Component: COPII vesicle coat; cytosol; endoplasmic reticulum; endoplasmic reticulum membrane; Golgi membrane; perinuclear region of cytoplasm; smooth endoplasmic reticulum membrane Molecular Function:protein binding; zinc ion binding Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class II; antigen processing and presentation of peptide antigen via MHC class I; COPII coating of Golgi vesicle; ER to Golgi vesicle-mediated transport; intracellular protein transport; vesicle-mediated transport Disease: Craniolenticulosutural Dysplasia |
| NCBI Summary: | The protein encoded by this gene is a member of the SEC23 subfamily of the SEC23/SEC24 family. It is part of a protein complex and found in the ribosome-free transitional face of the endoplasmic reticulum (ER) and associated vesicles. This protein has similarity to yeast Sec23p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The encoded protein is suggested to play a role in the ER-Golgi protein trafficking. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q15436 |
| NCBI GenInfo Identifier: | 143811354 |
| NCBI Gene ID: | 10484 |
| NCBI Accession: | Q15436.2 |
| UniProt Secondary Accession: | Q15436,Q8NE16, B2R5P4, B3KXI2, |
| UniProt Related Accession: | Q15436 |
| Molecular Weight: | 63,101 Da |
| NCBI Full Name: | Protein transport protein Sec23A |
| NCBI Synonym Full Names: | Sec23 homolog A, coat complex II component |
| NCBI Official Symbol: | SEC23A |
| NCBI Official Synonym Symbols: | CLSD |
| NCBI Protein Information: | protein transport protein Sec23A |
| UniProt Protein Name: | Protein transport protein Sec23A |
| UniProt Synonym Protein Names: | SEC23-related protein A |
| Protein Family: | SEC23-interacting protein |
| UniProt Gene Name: | SEC23A |
| UniProt Entry Name: | SC23A_HUMAN |