Anti-SAP130 Antibody (CAB13897)
- SKU:
- CAB13897
- Product type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
抗体名: | Anti-SAP130 Antibody |
抗体コード: | CAB13897 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Mouse |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 819-1048 of human SAP130 (NP_078821.2). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Mouse |
ポジティブサンプル: | Mouse brain |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 819-1048 of human SAP130 (NP_078821.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | LSMP TSDL PPGA SPRK KPRK QQHV ISTE EGDM METN STDD EKST AKSL LVKA EKRK SPPK EYID EEGV RYVP VRPR PPIT LLRH YRNP WKAA YHHF QRYS DVRV KEEK KAML QEIA NQKG VSCR AQGW KVHL CAAQ LLQL TNLE HDVY ERLT NLQE GIIP KKKA ATDD DLHR INEL IQGN MQRC KLVM DQIS EARD SMLK VLDH KDRV LKLL NKNG TVKK VSKL KRKE KV |
遺伝子ID: | 79595 |
Uniprot: | Q9H0E3 |
セルラーロケーション: | Nucleus |
計算された分子量: | 65kDa/110kDa/113kDa |
観察された分子量: | 150kDa |
同義語: | SAP130 |
バックグラウンド: |
UniProt Protein Function: | SAP130: Acts as a transcriptional repressor. May function in the assembly and/or enzymatic activity of the mSin3A corepressor complex or in mediating interactions between the complex and other regulatory complexes. Belongs to the SAP130 family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Transcription factor; Acetyltransferase Chromosomal Location of Human Ortholog: 2q14.3 Cellular Component: nucleoplasm Molecular Function:histone acetyltransferase activity; transcription coactivator activity Biological Process: establishment and/or maintenance of chromatin architecture; transcription, DNA-dependent; negative regulation of gene expression, epigenetic; gene expression; negative regulation of transcription from RNA polymerase II promoter; regulation of gene expression, epigenetic |
NCBI Summary: | SAP130 is a subunit of the histone deacetylase (see HDAC1; MIM 601241)-dependent SIN3A (MIM 607776) corepressor complex (Fleischer et al., 2003 [PubMed 12724404]).[supplied by OMIM, Mar 2008] |
UniProt Code: | Q9H0E3 |
NCBI GenInfo Identifier: | 74717977 |
NCBI Gene ID: | 79595 |
NCBI Accession: | Q9H0E3.1 |
UniProt Related Accession: | Q9H0E3 |
Molecular Weight: | |
NCBI Full Name: | Histone deacetylase complex subunit SAP130 |
NCBI Synonym Full Names: | Sin3A associated protein 130 |
NCBI Official Symbol: | SAP130 |
NCBI Protein Information: | histone deacetylase complex subunit SAP130 |
UniProt Protein Name: | Histone deacetylase complex subunit SAP130 |
UniProt Synonym Protein Names: | 130 kDa Sin3-associated polypeptide; Sin3-associated polypeptide p130 |
UniProt Gene Name: | SAP130 |
UniProt Entry Name: | SP130_HUMAN |