Anti-SAMHD1 抗体 (CAB7794)

Anti-SAMHD1 Antibody (CAB7794)[KO Validated]

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SKU:

CAB7794

Product type:

Antibody

Reactivity:

Human

Reactivity:

Mouse

Reactivity:

Rat

Host Species:

Rabbit

Isotype:

IgG

Antibody Type:

Polyclonal Antibody

Research Area:

Immunology

Description

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抗体名:	Anti-SAMHD1 Antibody [KO Validated]
抗体コード:	CAB7794
抗体サイズ:	20uL, 50uL, 100uL
申し込み:	WB IHC IF IP
反応性:	Human, Mouse, Rat
宿主種:	Rabbit
免疫原:	Recombinant fusion protein containing a sequence corresponding to amino acids 387-626 of human SAMHD1 (NP_056289.2).

免疫原:	Recombinant fusion protein containing a sequence corresponding to amino acids 387-626 of human SAMHD1 (NP_056289.2).
精製方法:	Affinity purification
ストレージバッファ:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
アイソタイプ:	IgG
順序:	TDAF LKAD DYIE ITGA GGKK YRIS TAID DMEA YTKL TDNI FLEI LYST DPKL KDAR EILK QIEY RNLF KYVG ETQP TGQI KIKR EDYE SLPK EVAS AKPK VLLD VKLK AEDF IVDV INMD YGMQ EKNP IDHV SFYC KTAP NRAI RITK NQVS QLLP EKFA EQLI RVYC KKVD RKSL YAAR QYFV QWCA DRNF TKPQ DGDV IAPL ITPQ KKEW NDST SVQN PTRL REAS KSRV QLFK DDPM
遺伝子ID:	25939
Uniprot:	Q9Y3Z3
セルラーロケーション:	Nucleus
計算された分子量:	63kDa/68kDa/72kDa
観察された分子量:	72kDa

同義語:	SAMHD1, CHBL2, DCIP, HDDC1, MOP-5, SBBI88
バックグラウンド:	This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome.

NCBI Summary:	This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome. [provided by RefSeq, Mar 2010]
UniProt Code:	Q9Y3Z3
NCBI GenInfo Identifier:	38016914
NCBI Gene ID:	25939
NCBI Accession:	NP_056289.2
UniProt Secondary Accession:	Q9Y3Z3,Q5JXG8, Q8N491, Q9H004, Q9H005, Q9H3U9, B4E2A5 E1P5V2,
UniProt Related Accession:	Q9Y3Z3
Molecular Weight:	68,122 Da
NCBI Full Name:	deoxynucleoside triphosphate triphosphohydrolase SAMHD1
NCBI Synonym Full Names:	SAM domain and HD domain 1
NCBI Official Symbol:	SAMHD1
NCBI Official Synonym Symbols:	DCIP; CHBL2; HDDC1; MOP-5; SBBI88
NCBI Protein Information:	deoxynucleoside triphosphate triphosphohydrolase SAMHD1
UniProt Protein Name:	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1
UniProt Synonym Protein Names:	Dendritic cell-derived IFNG-induced protein; DCIP; Monocyte protein 5; MOP-5; SAM domain and HD domain-containing protein 1
Protein Family:	Deoxynucleoside triphosphate triphosphohydrolase
UniProt Gene Name:	SAMHD1
UniProt Entry Name:	SAMH1_HUMAN

	Western blot analysis of extracts of various cell lines, using SAMHD1 antibody (CAB7794) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
	Western blot analysis of extracts from normal (control) and SAMHD1 knockout (KO) HeLa cells, using SAMHD1 antibody (CAB7794) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 3min.
	Immunohistochemistry of paraffin-embedded human liver cancer using [KO Validated] SAMHD1 Rabbit pAb (CAB7794) at dilution of 1:100 (40x lens).
	Immunofluorescence analysis of A549 cells using SAMHD1 antibody (CAB7794). Blue: DAPI for nuclear staining.
	Immunoprecipitation analysis of 200ug extracts of HeLa cells using 3ug SAMHD1 antibody (CAB7794). Western blot was performed from the immunoprecipitate using SAMHD1 antibody (CAB7794) at a dilition of 1:1000.