Anti-S1PR2 Antibody (CAB18205)
- SKU:
- CAB18205
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
Frequently bought together:
Description
| 抗体名: | Anti-S1PR2 Antibody |
| 抗体コード: | CAB18205 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant protein of human S1PR2 . |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | U-87MG, HeLa, Mouse lung, Mouse brain, Mouse spleen |
| 免疫原: | Recombinant protein of human S1PR2 . |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 9294 |
| Uniprot: | O95136 |
| セルラーロケーション: | |
| 計算された分子量: | 39kDa |
| 観察された分子量: | 38kDa |
 | Western blot - S1PR2 Polyclonal Antibody (CAB18205) |
| 同義語: | EDG5, H218, LPB2, S1P2, AGR16, EDG-5, DFNB68, Gpcr13, S1PR2 |
| バックグラウンド: | This gene encodes a member of the G protein-coupled receptors, as well as the EDG family of proteins. The encoded protein is a receptor for sphingosine 1-phosphate, which participates in cell proliferation, survival, and transcriptional activation. Defects in this gene have been associated with congenital profound deafness. |
| UniProt Protein Function: | EDG5: Receptor for the lysosphingolipid sphingosine 1- phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis. Belongs to the G-protein coupled receptor 1 family. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR; Membrane protein, integral; Lipid-binding Chromosomal Location of Human Ortholog: 19p13.2 Cellular Component: integral to membrane; plasma membrane Molecular Function:G-protein coupled receptor activity; G-protein-coupled receptor binding; integrin binding; lipid binding; protein binding Biological Process: actin cytoskeleton reorganization; activation of MAPK activity; filopodium formation; G-protein coupled receptor protein signaling pathway; positive regulation of cell proliferation |
| NCBI Summary: | This gene encodes a member of the G protein-coupled receptors, as well as the EDG family of proteins. The encoded protein is a receptor for sphingosine 1-phosphate, which participates in cell proliferation, survival, and transcriptional activation. Defects in this gene have been associated with congenital profound deafness. [provided by RefSeq, Mar 2016] |
| UniProt Code: | O95136 |
| NCBI GenInfo Identifier: | 38257367 |
| NCBI Gene ID: | 9294 |
| NCBI Accession: | O95136.2 |
| UniProt Secondary Accession: | O95136,Q86UN8, |
| UniProt Related Accession: | O95136 |
| Molecular Weight: | 38,867 Da |
| NCBI Full Name: | Sphingosine 1-phosphate receptor 2 |
| NCBI Synonym Full Names: | sphingosine-1-phosphate receptor 2 |
| NCBI Official Symbol: | S1PR2 |
| NCBI Official Synonym Symbols: | EDG5; H218; LPB2; S1P2; AGR16; EDG-5; DFNB68; Gpcr13 |
| NCBI Protein Information: | sphingosine 1-phosphate receptor 2 |
| UniProt Protein Name: | Sphingosine 1-phosphate receptor 2 |
| UniProt Synonym Protein Names: | Endothelial differentiation G-protein coupled receptor 5; Sphingosine 1-phosphate receptor Edg-5; S1P receptor Edg-5 |
| Protein Family: | Sphingosine 1-phosphate receptor |
| UniProt Gene Name: | S1PR2 |
| UniProt Entry Name: | S1PR2_HUMAN |