Anti-S100A5 Antibody (CAB14779)
- SKU:
- CAB14779
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-S100A5 Antibody |
抗体コード: | CAB14779 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC |
反応性: | Human |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-92 of human S100A5 (NP_002953.2). |
申し込み: | WB IHC |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:100 - 1:200 |
反応性: | Human |
ポジティブサンプル: | U-251MG |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-92 of human S100A5 (NP_002953.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | METP LEKA LTTM VTTF HKYS GREG SKLT LSRK ELKE LIKK ELCL GEMK ESSI DDLM KSLD KNSD QEID FKEY SVFL TMLC MAYN DFFL EDNK |
遺伝子ID: | 6276 |
Uniprot: | P33763 |
セルラーロケーション: | |
計算された分子量: | 10kDa/12kDa |
観察された分子量: | 11kDa |
同義語: | S100A5, S100D |
バックグラウンド: | The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein has a Ca2+ affinity 20- to 100-fold higher than the other S100 proteins studied under identical conditions. This protein also binds Zn2+ and Cu2+, and Cu2+ strongly which impairs the binding of Ca2+. This protein is expressed in very restricted regions of the adult brain. |
UniProt Protein Function: | S100A5: Binds calcium, zinc and copper. One subunit can simultaneously bind 2 calcium ions or 2 copper ions plus 1 zinc ion. Calcium and copper ions compete for the same binding sites. Belongs to the S-100 family. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 1q21 Cellular Component: cell soma; nucleus Molecular Function:protein homodimerization activity; copper ion binding; zinc ion binding; calcium ion binding |
NCBI Summary: | The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein has a Ca2+ affinity 20- to 100-fold higher than the other S100 proteins studied under identical conditions. This protein also binds Zn2+ and Cu2+, and Cu2+ strongly which impairs the binding of Ca2+. This protein is expressed in very restricted regions of the adult brain. [provided by RefSeq, Jul 2008] |
UniProt Code: | P33763 |
NCBI GenInfo Identifier: | 62739837 |
NCBI Gene ID: | 6276 |
NCBI Accession: | AAH93957.1 |
UniProt Secondary Accession: | P33763,Q5RHS3, |
UniProt Related Accession: | P33763 |
Molecular Weight: | 10,744 Da |
NCBI Full Name: | S100 calcium binding protein A5 |
NCBI Synonym Full Names: | S100 calcium binding protein A5 |
NCBI Official Symbol: | S100A5 |
NCBI Official Synonym Symbols: | S100D |
NCBI Protein Information: | protein S100-A5; S100 calcium-binding protein A5 |
UniProt Protein Name: | Protein S100-A5 |
UniProt Synonym Protein Names: | Protein S-100D; S100 calcium-binding protein A5 |
Protein Family: | Protein |
UniProt Gene Name: | S100A5 |
UniProt Entry Name: | S10A5_HUMAN |
View AllClose