Anti-S100A11 Antibody (CAB5486)[KO Validated]
- SKU:
- CAB5486
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-S100A11 Antibody [KO Validated] |
抗体コード: | CAB5486 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC IF IP |
反応性: | Human |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-105 of human S100A11 (NP_005611.1). |
申し込み: | WB IHC IF IP |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 IP 1:50 - 1:200 |
反応性: | Human |
ポジティブサンプル: | BxPC-3, BT-474, LOVO, 22Rv1, SKOV3, THP-1 |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-105 of human S100A11 (NP_005611.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MAKI SSPT ETER CIES LIAV FQKY AGKD GYNY TLSK TEFL SFMN TELA AFTK NQKD PGVL DRMM KKLD TNSD GQLD FSEF LNLI GGLA MACH DSFL KAVP SQKR T |
遺伝子ID: | 6282 |
Uniprot: | P31949 |
セルラーロケーション: | Cytoplasm, Nucleus |
計算された分子量: | 11kDa |
観察された分子量: | 12kDa |
同義語: | S100A11, HEL-S-43, MLN70, S100C |
バックグラウンド: | The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. |
UniProt Protein Function: | S100A11: a calcium-binding regulatory protein of the S-100 family. Interacts with the N-termini of annexins A1. May regulate fusion processes such as endo- and exocytosis. Increases in the early stage of pancreatic carcinogenesis and decreases during subsequent progression to cancer. Increased expression in anaplastic large cell lymphoma. |
UniProt Protein Details: | Protein type:Calcium-binding; DNA replication; Cell cycle regulation Chromosomal Location of Human Ortholog: 1q21 Cellular Component: cytoplasm; extracellular space; nucleus; ruffle Molecular Function:calcium-dependent protein binding; protein binding; protein homodimerization activity Biological Process: negative regulation of cell proliferation; negative regulation of DNA replication; signal transduction |
NCBI Summary: | The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. [provided by RefSeq, Jul 2008] |
UniProt Code: | P31949 |
NCBI GenInfo Identifier: | 1710818 |
NCBI Gene ID: | 6282 |
NCBI Accession: | P31949.2 |
UniProt Secondary Accession: | P31949,Q5VTK0, |
UniProt Related Accession: | P31949 |
Molecular Weight: | 11,740 Da |
NCBI Full Name: | Protein S100-A11 |
NCBI Synonym Full Names: | S100 calcium binding protein A11 |
NCBI Official Symbol: | S100A11 |
NCBI Official Synonym Symbols: | MLN70; S100C; HEL-S-43 |
NCBI Protein Information: | protein S100-A11 |
UniProt Protein Name: | Protein S100-A11 |
UniProt Synonym Protein Names: | Calgizzarin; Metastatic lymph node gene 70 protein; MLN 70 |
Protein Family: | Protein |
UniProt Gene Name: | S100A11 |
UniProt Entry Name: | S10AB_HUMAN |
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