Anti-RYBP Antibody (CAB14605)
- SKU:
- CAB14605
- Product type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Death
Frequently bought together:
Description
| 抗体名: | Anti-RYBP Antibody |
| 抗体コード: | CAB14605 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of human RYBP (NP_036366.3). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Mouse, Rat |
| ポジティブサンプル: | Mouse brain, Rat brain |
| 免疫原: | A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of human RYBP (NP_036366.3). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | PSVT KKNT NKKT KPKS DILK DPPS EANS IQSA NATT KTSE TNHT SRPR LKNV DRST AQQL AVTV GNVT VIIT DFKE KTRS SSTS SSTV TSSA GSEQ QNQS SSGS ESTD KGSS RSST PKGD MSAV NDES F |
| 遺伝子ID: | 23429 |
| Uniprot: | Q8N488 |
| セルラーロケーション: | Cytoplasm, Nucleus, nucleoplasm |
| 計算された分子量: | 24kDa |
| 観察された分子量: | 33kDa |
| 同義語: | RYBP, AAP1, APAP-1, DEDAF, YEAF1 |
| バックグラウンド: |
| UniProt Protein Function: | RYBP: Inhibits ubiquitination and subsequent degradation of TP53, and thereby plays a role in regulating transcription of TP53 target genes. May be implicated in the regulation of the transcription as a repressor of the transcriptional activity of E4TF1. May bind to DNA. Promotes apoptosis. |
| UniProt Protein Details: | Protein type:Transcription, coactivator/corepressor Chromosomal Location of Human Ortholog: 3p13 Cellular Component: nucleoplasm; PcG protein complex Molecular Function:protein binding Biological Process: multicellular organismal development |
| UniProt Code: | Q8N488 |
| NCBI GenInfo Identifier: | 78102506 |
| NCBI Gene ID: | 23429 |
| NCBI Accession: | Q8N488.2 |
| UniProt Secondary Accession: | Q8N488,Q9P2W5, Q9UMW4, |
| UniProt Related Accession: | Q8N488 |
| Molecular Weight: | 24,822 Da |
| NCBI Full Name: | RING1 and YY1-binding protein |
| NCBI Synonym Full Names: | RING1 and YY1 binding protein |
| NCBI Official Symbol: | RYBP |
| NCBI Official Synonym Symbols: | AAP1; DEDAF; YEAF1; APAP-1 |
| NCBI Protein Information: | RING1 and YY1-binding protein |
| UniProt Protein Name: | RING1 and YY1-binding protein |
| UniProt Synonym Protein Names: | Apoptin-associating protein 1; APAP-1; Death effector domain-associated factor; DED-associated factor; YY1 and E4TF1-associated factor 1 |
| Protein Family: | RING1 and YY1-binding protein |
| UniProt Gene Name: | RYBP |
| UniProt Entry Name: | RYBP_HUMAN |
 | Western blot analysis of extracts of various cell lines, using RYBP Rabbit pAb (CAB14605) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
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