Anti-RXRB Antibody (CAB18119)
- SKU:
- CAB18119
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
Frequently bought together:
Description
| 抗体名: | Anti-RXRB Antibody |
| 抗体コード: | CAB18119 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant protein of human RXRB. |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | mouse brain, rat brain |
| 免疫原: | Recombinant protein of human RXRB. |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 6257 |
| Uniprot: | P28702 |
| セルラーロケーション: | |
| 計算された分子量: | |
| 観察された分子量: | 70kDa |
 | Western blot - RXRB Polyclonal Antibody (CAB18119) |
| 同義語: | DAUDI6, H-2RIIBP, NR2B2, RCoR-1, RXRB |
| バックグラウンド: |
| UniProt Protein Function: | RXRB: Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. Specifically binds 9-cis retinoic acid (9C-RA). Homodimer. Heterodimer with a RAR molecule. Binds DNA preferentially as a RAR/RXR heterodimer. Expressed in a variety of tumor cell lines. Belongs to the nuclear hormone receptor family. NR2 subfamily. |
| UniProt Protein Details: | Protein type:DNA-binding; Nuclear receptor Chromosomal Location of Human Ortholog: 6p21.3 Cellular Component: nucleoplasm; nucleus Molecular Function:ligand-dependent nuclear receptor activity; protein binding; transcription coactivator activity Biological Process: positive regulation of transcription from RNA polymerase II promoter; transcription initiation from RNA polymerase II promoter |
| NCBI Summary: | This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA). The encoded protein forms homodimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene lies within the major histocompatibility complex (MHC) class II region on chromosome 6. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012] |
| UniProt Code: | P28702 |
| NCBI GenInfo Identifier: | 1350911 |
| NCBI Gene ID: | 6257 |
| NCBI Accession: | P28702.2 |
| UniProt Secondary Accession: | P28702,P28703, Q59G65, Q5JP92, Q5STQ1, |
| UniProt Related Accession: | P28702 |
| Molecular Weight: | 57,365 Da |
| NCBI Full Name: | Retinoic acid receptor RXR-beta |
| NCBI Synonym Full Names: | retinoid X receptor beta |
| NCBI Official Symbol: | RXRB |
| NCBI Official Synonym Symbols: | NR2B2; DAUDI6; RCoR-1; H-2RIIBP |
| NCBI Protein Information: | retinoic acid receptor RXR-beta |
| UniProt Protein Name: | Retinoic acid receptor RXR-beta |
| UniProt Synonym Protein Names: | Nuclear receptor subfamily 2 group B member 2; Retinoid X receptor beta |
| Protein Family: | Retinoic acid receptor |
| UniProt Gene Name: | RXRB |
| UniProt Entry Name: | RXRB_HUMAN |