Anti-RXFP2 Antibody (CAB14301)
- SKU:
- CAB14301
- Product type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-RXFP2 Antibody |
| 抗体コード: | CAB14301 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 80-180 of human RXFP2 (NP_570718.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Mouse, Rat |
| ポジティブサンプル: | Mouse kidney, Rat kidney |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 80-180 of human RXFP2 (NP_570718.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | CGDT SGWA TIFG TVHG NANS VALT QECF LKQY PQCC DCKE TELE CVNG DLKS VPMI SNNV TLLS LKKN KIHS LPDK VFIK YTKL KKIF LQHN CIRH ISRK A |
| 遺伝子ID: | 122042 |
| Uniprot: | Q8WXD0 |
| セルラーロケーション: | Cell membrane, Multi-pass membrane protein |
| 計算された分子量: | 83kDa/86kDa |
| 観察された分子量: | 86kDa |
| 同義語: | RXFP2, GPR106, GREAT, INSL3R, LGR8, LGR8.1, RXFPR2 |
| バックグラウンド: | This gene encodes a member of the GPCR (G protein-coupled, 7-transmembrane receptor) family. Mutations in this gene are associated with cryptorchidism. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| UniProt Protein Function: | LGR8: the relaxin receptor is a G-protein coupled receptor (GPCR) that leads to the stimulation of adenylate cyclase and an increase of cAMP. May also be a receptor for Leydig insulin-like peptide (INSL3). |
| UniProt Protein Details: | Protein type:Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integral; GPCR, family 1 Chromosomal Location of Human Ortholog: 13q13.1 Cellular Component: plasma membrane Molecular Function:G-protein coupled receptor activity Biological Process: G-protein signaling, coupled to cAMP nucleotide second messenger Disease: Cryptorchidism, Unilateral Or Bilateral |
| NCBI Summary: | This gene encodes a member of the GPCR (G protein-coupled, 7-transmembrane receptor) family. Mutations in this gene are associated with cryptorchidism. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009] |
| UniProt Code: | Q8WXD0 |
| NCBI GenInfo Identifier: | 21362625 |
| NCBI Gene ID: | 122042 |
| NCBI Accession: | Q8WXD0.1 |
| UniProt Secondary Accession: | Q8WXD0,Q3KU23, B1ALE9, |
| UniProt Related Accession: | Q8WXD0 |
| Molecular Weight: | 83,736 Da |
| NCBI Full Name: | Relaxin receptor 2 |
| NCBI Synonym Full Names: | relaxin/insulin like family peptide receptor 2 |
| NCBI Official Symbol: | RXFP2 |
| NCBI Official Synonym Symbols: | LGR8; GREAT; GPR106; INSL3R; LGR8.1; RXFPR2 |
| NCBI Protein Information: | relaxin receptor 2 |
| UniProt Protein Name: | Relaxin receptor 2 |
| UniProt Synonym Protein Names: | G-protein coupled receptor 106; G-protein coupled receptor affecting testicular descent; Leucine-rich repeat-containing G-protein coupled receptor 8; Relaxin family peptide receptor 2 |
| Protein Family: | Relaxin receptor |
| UniProt Gene Name: | RXFP2 |
| UniProt Entry Name: | RXFP2_HUMAN |
 | Western blot analysis of extracts of various cell lines, using RXFP2 antibody (CAB14301) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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