Anti-RUFY1 Antibody (CAB7836)
- SKU:
- CAB7836
- Product type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-RUFY1 Antibody |
抗体コード: | CAB7836 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC |
反応性: | Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 439-708 of human RUFY1 (NP_079434.3). |
申し込み: | WB IHC |
推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
反応性: | Mouse, Rat |
ポジティブサンプル: | Mouse kidney, Mouse heart, Rat lung |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 439-708 of human RUFY1 (NP_079434.3). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | EKDT HEKQ DTLV ALRQ QLEE VKAI NLQM FHKA QNAE SSLQ QKNE AITS FEGK TNQV MSSM KQME ERLQ HSER ARQG AEER SHKL QQEL GGRI GALQ LQLS QLHE QCSS LEKE LKSE KEQR QALQ RELQ HEKD TSSL LRME LQQV EGLK KELR ELQD EKAE LQKI CEEQ EQAL QEMG LHLS QSKL KMED IKEV NQAL KGHA WLKD DEAT HCRQ CEKE FSIS RRKH HCRN CGHI FCNT CSSN ELAL PSYP KPVR VCDS CHTL LLQR CSST AS |
遺伝子ID: | 80230 |
Uniprot: | Q96T51 |
セルラーロケーション: | Cytoplasm, Early endosome membrane, Peripheral membrane protein |
計算された分子量: | 44kDa/69kDa/79kDa |
観察された分子量: | 80kDa |
同義語: | RUFY1, RABIP4, ZFYVE12 |
バックグラウンド: | This gene encodes a protein that contains a RUN domain and a FYVE-type zinc finger domain. The encoded protein binds to phosphatidylinositol-3-phosphate (PI3P) and plays a role in early endosomal trafficking, tethering and fusion through interactions with small GTPases including Rab4, Rab5 and Rab14. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
UniProt Protein Function: | RUFY1: Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in early endosomal trafficking. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Ubiquitin conjugating system Chromosomal Location of Human Ortholog: 5q35.3 Cellular Component: intracellular membrane-bound organelle; early endosome membrane; cytoplasm; nucleus Molecular Function:protein binding; zinc ion binding; lipid binding; protein transporter activity Biological Process: protein transport; regulation of endocytosis; endocytosis |
NCBI Summary: | This gene encodes a protein that contains a RUN domain and a FYVE-type zinc finger domain. The encoded protein binds to phosphatidylinositol-3-phosphate (PI3P) and plays a role in early endosomal trafficking, tethering and fusion through interactions with small GTPases including Rab4, Rab5 and Rab14. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011] |
UniProt Code: | Q96T51 |
NCBI GenInfo Identifier: | 94721332 |
NCBI Gene ID: | 80230 |
NCBI Accession: | NP_001035541.1 |
UniProt Secondary Accession: | Q96T51,Q59FF3, Q71S93, Q9H6I3, |
UniProt Related Accession: | Q96T51 |
Molecular Weight: | 79,818 Da |
NCBI Full Name: | RUN and FYVE domain-containing protein 1 isoform b |
NCBI Synonym Full Names: | RUN and FYVE domain containing 1 |
NCBI Official Symbol: | RUFY1 |
NCBI Official Synonym Symbols: | RABIP4; ZFYVE12 |
NCBI Protein Information: | RUN and FYVE domain-containing protein 1; la-binding protein 1; FYVE-finger protein EIP1; rab4-interacting protein; zinc finger FYVE domain-containing protein 12 |
UniProt Protein Name: | RUN and FYVE domain-containing protein 1 |
UniProt Synonym Protein Names: | FYVE-finger protein EIP1; La-binding protein 1; Rab4-interacting protein; Zinc finger FYVE domain-containing protein 12 |
Protein Family: | RUN and FYVE domain-containing protein |
UniProt Gene Name: | RUFY1 |
UniProt Entry Name: | RUFY1_HUMAN |
View AllClose